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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ATP7B All Species: 4.24
Human Site: S1132 Identified Species: 8.48
UniProt: P35670 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0.27
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P35670 NP_000044.2 1465 157263 S1132 S H L N E A G S L P A E K D A
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001103242 1333 143814 E1041 S D A M T D H E M K G Q T A I
Dog Lupus familis XP_860306 1504 164598 Q1153 I K N A S L V Q I G A N N E Q
Cat Felis silvestris
Mouse Mus musculus Q64446 1462 157279 E1134 V G N P P T G E G A G P Q T F
Rat Rattus norvegicus Q64535 1451 155972 E1125 V G N P P I G E G T G P Q T F
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001507266 1609 174606 Q1259 L K N A S L V Q I D A S P E Q
Chicken Gallus gallus XP_417073 1516 163625 S1192 G Y I C K P S S S S S H I Y S
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_001036185 1482 159963 I1134 H N A V L I Q I S D A R A H S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_572756 1254 136064 S965 L V C M F A V S D M V K P E A
Honey Bee Apis mellifera XP_395837 1274 139224 V985 C T A V L A A V N N V L V A M
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9SH30 995 108318 I706 E H P L A K A I V E Y A K K F
Baker's Yeast Sacchar. cerevisiae P38995 1004 109810 Y715 C Q V N G N T Y D I C I G N E
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 88 56.5 N.A. 82.8 82.3 N.A. 49.7 68 N.A. 56.3 N.A. 40.8 42.5 N.A. N.A.
Protein Similarity: 100 N.A. 89.3 72.5 N.A. 89.9 88.8 N.A. 65.1 80.9 N.A. 71.5 N.A. 57.5 59.3 N.A. N.A.
P-Site Identity: 100 N.A. 6.6 6.6 N.A. 6.6 6.6 N.A. 6.6 6.6 N.A. 6.6 N.A. 20 6.6 N.A. N.A.
P-Site Similarity: 100 N.A. 20 20 N.A. 13.3 13.3 N.A. 20 40 N.A. 20 N.A. 33.3 6.6 N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. 31.6 26.6 N.A.
Protein Similarity: N.A. N.A. N.A. 46.2 44.1 N.A.
P-Site Identity: N.A. N.A. N.A. 13.3 6.6 N.A.
P-Site Similarity: N.A. N.A. N.A. 20 20 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 25 17 9 25 17 0 0 9 34 9 9 17 17 % A
% Cys: 17 0 9 9 0 0 0 0 0 0 9 0 0 0 0 % C
% Asp: 0 9 0 0 0 9 0 0 17 17 0 0 0 9 0 % D
% Glu: 9 0 0 0 9 0 0 25 0 9 0 9 0 25 9 % E
% Phe: 0 0 0 0 9 0 0 0 0 0 0 0 0 0 25 % F
% Gly: 9 17 0 0 9 0 25 0 17 9 25 0 9 0 0 % G
% His: 9 17 0 0 0 0 9 0 0 0 0 9 0 9 0 % H
% Ile: 9 0 9 0 0 17 0 17 17 9 0 9 9 0 9 % I
% Lys: 0 17 0 0 9 9 0 0 0 9 0 9 17 9 0 % K
% Leu: 17 0 9 9 17 17 0 0 9 0 0 9 0 0 0 % L
% Met: 0 0 0 17 0 0 0 0 9 9 0 0 0 0 9 % M
% Asn: 0 9 34 17 0 9 0 0 9 9 0 9 9 9 0 % N
% Pro: 0 0 9 17 17 9 0 0 0 9 0 17 17 0 0 % P
% Gln: 0 9 0 0 0 0 9 17 0 0 0 9 17 0 17 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 9 0 0 0 % R
% Ser: 17 0 0 0 17 0 9 25 17 9 9 9 0 0 17 % S
% Thr: 0 9 0 0 9 9 9 0 0 9 0 0 9 17 0 % T
% Val: 17 9 9 17 0 0 25 9 9 0 17 0 9 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 9 0 0 0 0 0 9 0 0 9 0 0 9 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _