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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ATP7B
All Species:
2.42
Human Site:
S254
Identified Species:
4.85
UniProt:
P35670
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P35670
NP_000044.2
1465
157263
S254
E
T
L
G
H
Q
G
S
H
V
V
T
L
Q
L
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001103242
1333
143814
E247
N
Q
N
F
N
N
S
E
T
L
G
H
Q
G
R
Dog
Lupus familis
XP_860306
1504
164598
S275
Q
R
S
P
S
Y
T
S
D
S
T
V
T
F
I
Cat
Felis silvestris
Mouse
Mus musculus
Q64446
1462
157279
E257
V
Q
I
S
N
H
F
E
T
L
G
H
Q
G
S
Rat
Rattus norvegicus
Q64535
1451
155972
N253
E
T
P
G
H
Q
Q
N
H
L
A
T
L
P
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507266
1609
174606
V277
E
D
S
N
S
P
Q
V
G
E
I
M
L
K
I
Chicken
Gallus gallus
XP_417073
1516
163625
T322
L
V
A
N
K
S
S
T
A
A
V
T
V
H
I
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001036185
1482
159963
K246
K
S
K
P
R
Q
L
K
L
S
A
S
E
V
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_572756
1254
136064
P174
S
Q
S
P
S
P
A
P
A
S
S
P
K
K
R
Honey Bee
Apis mellifera
XP_395837
1274
139224
Q194
D
N
D
V
T
A
E
Q
I
S
G
F
I
E
E
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9SH30
995
108318
Baker's Yeast
Sacchar. cerevisiae
P38995
1004
109810
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
88
56.5
N.A.
82.8
82.3
N.A.
49.7
68
N.A.
56.3
N.A.
40.8
42.5
N.A.
N.A.
Protein Similarity:
100
N.A.
89.3
72.5
N.A.
89.9
88.8
N.A.
65.1
80.9
N.A.
71.5
N.A.
57.5
59.3
N.A.
N.A.
P-Site Identity:
100
N.A.
0
6.6
N.A.
0
60
N.A.
13.3
13.3
N.A.
6.6
N.A.
0
0
N.A.
N.A.
P-Site Similarity:
100
N.A.
13.3
20
N.A.
20
73.3
N.A.
33.3
33.3
N.A.
26.6
N.A.
6.6
20
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
31.6
26.6
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
46.2
44.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
0
0
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
9
0
0
9
9
0
17
9
17
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
9
9
9
0
0
0
0
0
9
0
0
0
0
0
0
% D
% Glu:
25
0
0
0
0
0
9
17
0
9
0
0
9
9
17
% E
% Phe:
0
0
0
9
0
0
9
0
0
0
0
9
0
9
0
% F
% Gly:
0
0
0
17
0
0
9
0
9
0
25
0
0
17
0
% G
% His:
0
0
0
0
17
9
0
0
17
0
0
17
0
9
0
% H
% Ile:
0
0
9
0
0
0
0
0
9
0
9
0
9
0
25
% I
% Lys:
9
0
9
0
9
0
0
9
0
0
0
0
9
17
0
% K
% Leu:
9
0
9
0
0
0
9
0
9
25
0
0
25
0
17
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
9
0
0
0
% M
% Asn:
9
9
9
17
17
9
0
9
0
0
0
0
0
0
0
% N
% Pro:
0
0
9
25
0
17
0
9
0
0
0
9
0
9
0
% P
% Gln:
9
25
0
0
0
25
17
9
0
0
0
0
17
9
0
% Q
% Arg:
0
9
0
0
9
0
0
0
0
0
0
0
0
0
17
% R
% Ser:
9
9
25
9
25
9
17
17
0
34
9
9
0
0
9
% S
% Thr:
0
17
0
0
9
0
9
9
17
0
9
25
9
0
0
% T
% Val:
9
9
0
9
0
0
0
9
0
9
17
9
9
9
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
9
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _