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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ATP7B
All Species:
19.39
Human Site:
S382
Identified Species:
38.79
UniProt:
P35670
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P35670
NP_000044.2
1465
157263
S382
H
S
I
E
G
M
I
S
Q
L
E
G
V
Q
Q
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001103242
1333
143814
S370
I
W
A
K
S
P
Q
S
T
R
A
V
A
P
Q
Dog
Lupus familis
XP_860306
1504
164598
S400
Q
S
I
E
G
V
I
S
K
K
E
G
V
K
S
Cat
Felis silvestris
Mouse
Mus musculus
Q64446
1462
157279
S384
Q
P
I
E
D
M
L
S
Q
R
K
G
V
Q
Q
Rat
Rattus norvegicus
Q64535
1451
155972
S378
Q
P
M
E
D
M
L
S
Q
M
K
G
V
Q
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507266
1609
174606
S409
L
N
I
E
G
S
L
S
A
L
P
S
V
H
S
Chicken
Gallus gallus
XP_417073
1516
163625
S446
Q
S
I
E
G
T
M
S
Q
R
Q
G
V
Q
H
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001036185
1482
159963
T369
E
I
H
I
E
G
M
T
C
G
S
C
V
Q
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_572756
1254
136064
A296
E
I
M
G
M
T
C
A
S
C
V
N
K
I
E
Honey Bee
Apis mellifera
XP_395837
1274
139224
I317
L
G
F
P
T
T
L
I
E
E
P
G
T
G
E
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9SH30
995
108318
S38
R
D
G
G
G
G
S
S
S
E
T
A
A
F
E
Baker's Yeast
Sacchar. cerevisiae
P38995
1004
109810
D47
N
E
C
Q
V
T
Y
D
N
E
V
T
A
D
S
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
88
56.5
N.A.
82.8
82.3
N.A.
49.7
68
N.A.
56.3
N.A.
40.8
42.5
N.A.
N.A.
Protein Similarity:
100
N.A.
89.3
72.5
N.A.
89.9
88.8
N.A.
65.1
80.9
N.A.
71.5
N.A.
57.5
59.3
N.A.
N.A.
P-Site Identity:
100
N.A.
13.3
60
N.A.
60
53.3
N.A.
40
60
N.A.
13.3
N.A.
0
6.6
N.A.
N.A.
P-Site Similarity:
100
N.A.
20
80
N.A.
73.3
80
N.A.
53.3
73.3
N.A.
26.6
N.A.
20
26.6
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
31.6
26.6
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
46.2
44.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
9
0
0
0
0
9
9
0
9
9
25
0
0
% A
% Cys:
0
0
9
0
0
0
9
0
9
9
0
9
0
0
0
% C
% Asp:
0
9
0
0
17
0
0
9
0
0
0
0
0
9
0
% D
% Glu:
17
9
0
50
9
0
0
0
9
25
17
0
0
0
25
% E
% Phe:
0
0
9
0
0
0
0
0
0
0
0
0
0
9
0
% F
% Gly:
0
9
9
17
42
17
0
0
0
9
0
50
0
9
0
% G
% His:
9
0
9
0
0
0
0
0
0
0
0
0
0
9
9
% H
% Ile:
9
17
42
9
0
0
17
9
0
0
0
0
0
9
0
% I
% Lys:
0
0
0
9
0
0
0
0
9
9
17
0
9
9
0
% K
% Leu:
17
0
0
0
0
0
34
0
0
17
0
0
0
0
0
% L
% Met:
0
0
17
0
9
25
17
0
0
9
0
0
0
0
0
% M
% Asn:
9
9
0
0
0
0
0
0
9
0
0
9
0
0
0
% N
% Pro:
0
17
0
9
0
9
0
0
0
0
17
0
0
9
0
% P
% Gln:
34
0
0
9
0
0
9
0
34
0
9
0
0
42
34
% Q
% Arg:
9
0
0
0
0
0
0
0
0
25
0
0
0
0
0
% R
% Ser:
0
25
0
0
9
9
9
67
17
0
9
9
0
0
34
% S
% Thr:
0
0
0
0
9
34
0
9
9
0
9
9
9
0
0
% T
% Val:
0
0
0
0
9
9
0
0
0
0
17
9
59
0
0
% V
% Trp:
0
9
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
9
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _