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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ATP7B
All Species:
7.58
Human Site:
S428
Identified Species:
15.15
UniProt:
P35670
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.18
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P35670
NP_000044.2
1465
157263
S428
G
F
E
A
S
V
V
S
E
S
C
S
T
N
P
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001103242
1333
143814
G415
V
L
V
A
L
M
A
G
K
A
E
V
K
Y
D
Dog
Lupus familis
XP_860306
1504
164598
I445
M
G
F
D
A
A
L
I
F
P
C
P
P
D
I
Cat
Felis silvestris
Mouse
Mus musculus
Q64446
1462
157279
S430
G
F
E
V
S
V
N
S
E
T
F
T
I
N
P
Rat
Rattus norvegicus
Q64535
1451
155972
P424
G
F
E
V
S
V
N
P
E
N
I
T
T
N
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507266
1609
174606
R458
Q
F
R
V
S
L
A
R
E
N
T
S
D
L
N
Chicken
Gallus gallus
XP_417073
1516
163625
T492
G
F
D
A
S
L
L
T
G
N
S
V
L
S
S
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001036185
1482
159963
R414
L
T
S
P
E
E
L
R
A
A
I
E
D
M
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_572756
1254
136064
A341
G
P
R
S
I
C
E
A
I
E
A
L
G
F
E
Honey Bee
Apis mellifera
XP_395837
1274
139224
T362
S
A
V
V
A
L
A
T
Q
R
G
K
F
K
Y
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9SH30
995
108318
V83
L
P
G
I
H
D
A
V
I
D
A
L
N
N
R
Baker's Yeast
Sacchar. cerevisiae
P38995
1004
109810
G92
S
V
Q
G
M
T
C
G
S
C
V
S
T
V
T
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
88
56.5
N.A.
82.8
82.3
N.A.
49.7
68
N.A.
56.3
N.A.
40.8
42.5
N.A.
N.A.
Protein Similarity:
100
N.A.
89.3
72.5
N.A.
89.9
88.8
N.A.
65.1
80.9
N.A.
71.5
N.A.
57.5
59.3
N.A.
N.A.
P-Site Identity:
100
N.A.
6.6
6.6
N.A.
60
53.3
N.A.
26.6
26.6
N.A.
0
N.A.
6.6
0
N.A.
N.A.
P-Site Similarity:
100
N.A.
26.6
26.6
N.A.
73.3
66.6
N.A.
40
66.6
N.A.
13.3
N.A.
20
26.6
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
31.6
26.6
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
46.2
44.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
6.6
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
9
0
25
17
9
34
9
9
17
17
0
0
0
0
% A
% Cys:
0
0
0
0
0
9
9
0
0
9
17
0
0
0
0
% C
% Asp:
0
0
9
9
0
9
0
0
0
9
0
0
17
9
9
% D
% Glu:
0
0
25
0
9
9
9
0
34
9
9
9
0
0
9
% E
% Phe:
0
42
9
0
0
0
0
0
9
0
9
0
9
9
0
% F
% Gly:
42
9
9
9
0
0
0
17
9
0
9
0
9
0
9
% G
% His:
0
0
0
0
9
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
9
9
0
0
9
17
0
17
0
9
0
9
% I
% Lys:
0
0
0
0
0
0
0
0
9
0
0
9
9
9
0
% K
% Leu:
17
9
0
0
9
25
25
0
0
0
0
17
9
9
0
% L
% Met:
9
0
0
0
9
9
0
0
0
0
0
0
0
9
0
% M
% Asn:
0
0
0
0
0
0
17
0
0
25
0
0
9
34
9
% N
% Pro:
0
17
0
9
0
0
0
9
0
9
0
9
9
0
17
% P
% Gln:
9
0
9
0
0
0
0
0
9
0
0
0
0
0
0
% Q
% Arg:
0
0
17
0
0
0
0
17
0
9
0
0
0
0
17
% R
% Ser:
17
0
9
9
42
0
0
17
9
9
9
25
0
9
9
% S
% Thr:
0
9
0
0
0
9
0
17
0
9
9
17
25
0
9
% T
% Val:
9
9
17
34
0
25
9
9
0
0
9
17
0
9
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
9
9
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _