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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ATP7B
All Species:
25.76
Human Site:
S876
Identified Species:
51.52
UniProt:
P35670
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P35670
NP_000044.2
1465
157263
S876
G
S
T
V
I
A
G
S
I
N
A
H
G
S
V
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001103242
1333
143814
I798
Y
F
V
P
L
I
I
I
M
S
T
L
T
L
V
Dog
Lupus familis
XP_860306
1504
164598
S897
G
S
T
V
I
A
G
S
I
N
Q
N
G
S
L
Cat
Felis silvestris
Mouse
Mus musculus
Q64446
1462
157279
S878
G
S
I
V
I
A
G
S
I
N
A
H
G
S
V
Rat
Rattus norvegicus
Q64535
1451
155972
S869
G
S
I
V
I
A
G
S
I
N
A
H
G
S
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507266
1609
174606
S1003
G
S
T
V
I
A
G
S
I
N
Q
N
G
S
L
Chicken
Gallus gallus
XP_417073
1516
163625
S936
G
S
T
V
I
A
G
S
I
N
A
H
G
S
V
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001036185
1482
159963
S878
G
S
T
V
I
A
G
S
I
N
Q
N
G
S
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_572756
1254
136064
A722
M
V
A
T
G
T
G
A
I
N
G
V
L
V
K
Honey Bee
Apis mellifera
XP_395837
1274
139224
V743
A
F
R
S
A
L
C
V
L
A
I
A
C
P
C
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9SH30
995
108318
G464
T
G
E
E
E
I
D
G
R
L
I
Q
K
N
D
Baker's Yeast
Sacchar. cerevisiae
P38995
1004
109810
K473
E
S
I
L
V
P
K
K
T
G
F
P
V
I
A
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
88
56.5
N.A.
82.8
82.3
N.A.
49.7
68
N.A.
56.3
N.A.
40.8
42.5
N.A.
N.A.
Protein Similarity:
100
N.A.
89.3
72.5
N.A.
89.9
88.8
N.A.
65.1
80.9
N.A.
71.5
N.A.
57.5
59.3
N.A.
N.A.
P-Site Identity:
100
N.A.
6.6
80
N.A.
93.3
93.3
N.A.
80
100
N.A.
80
N.A.
20
0
N.A.
N.A.
P-Site Similarity:
100
N.A.
26.6
93.3
N.A.
93.3
93.3
N.A.
93.3
100
N.A.
93.3
N.A.
26.6
6.6
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
31.6
26.6
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
46.2
44.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
6.6
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
0
9
0
9
59
0
9
0
9
34
9
0
0
9
% A
% Cys:
0
0
0
0
0
0
9
0
0
0
0
0
9
0
9
% C
% Asp:
0
0
0
0
0
0
9
0
0
0
0
0
0
0
9
% D
% Glu:
9
0
9
9
9
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
17
0
0
0
0
0
0
0
0
9
0
0
0
0
% F
% Gly:
59
9
0
0
9
0
67
9
0
9
9
0
59
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
34
0
0
0
% H
% Ile:
0
0
25
0
59
17
9
9
67
0
17
0
0
9
0
% I
% Lys:
0
0
0
0
0
0
9
9
0
0
0
0
9
0
9
% K
% Leu:
0
0
0
9
9
9
0
0
9
9
0
9
9
9
25
% L
% Met:
9
0
0
0
0
0
0
0
9
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
67
0
25
0
9
0
% N
% Pro:
0
0
0
9
0
9
0
0
0
0
0
9
0
9
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
25
9
0
0
0
% Q
% Arg:
0
0
9
0
0
0
0
0
9
0
0
0
0
0
0
% R
% Ser:
0
67
0
9
0
0
0
59
0
9
0
0
0
59
0
% S
% Thr:
9
0
42
9
0
9
0
0
9
0
9
0
9
0
0
% T
% Val:
0
9
9
59
9
0
0
9
0
0
0
9
9
9
42
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
9
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _