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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ATP7B
All Species:
3.33
Human Site:
T433
Identified Species:
6.67
UniProt:
P35670
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P35670
NP_000044.2
1465
157263
T433
V
V
S
E
S
C
S
T
N
P
L
G
N
H
S
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001103242
1333
143814
K420
M
A
G
K
A
E
V
K
Y
D
P
E
V
I
Q
Dog
Lupus familis
XP_860306
1504
164598
P450
A
L
I
F
P
C
P
P
D
I
N
E
P
L
V
Cat
Felis silvestris
Mouse
Mus musculus
Q64446
1462
157279
I435
V
N
S
E
T
F
T
I
N
P
V
R
N
F
K
Rat
Rattus norvegicus
Q64535
1451
155972
T429
V
N
P
E
N
I
T
T
N
R
V
S
S
G
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507266
1609
174606
D463
L
A
R
E
N
T
S
D
L
N
T
P
S
S
P
Chicken
Gallus gallus
XP_417073
1516
163625
L497
L
L
T
G
N
S
V
L
S
S
V
G
S
T
S
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001036185
1482
159963
D419
E
L
R
A
A
I
E
D
M
G
F
D
A
F
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_572756
1254
136064
G346
C
E
A
I
E
A
L
G
F
E
A
K
L
M
T
Honey Bee
Apis mellifera
XP_395837
1274
139224
F367
L
A
T
Q
R
G
K
F
K
Y
D
V
E
K
I
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9SH30
995
108318
N88
D
A
V
I
D
A
L
N
N
R
A
Q
I
L
F
Baker's Yeast
Sacchar. cerevisiae
P38995
1004
109810
T97
T
C
G
S
C
V
S
T
V
T
K
Q
V
E
G
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
88
56.5
N.A.
82.8
82.3
N.A.
49.7
68
N.A.
56.3
N.A.
40.8
42.5
N.A.
N.A.
Protein Similarity:
100
N.A.
89.3
72.5
N.A.
89.9
88.8
N.A.
65.1
80.9
N.A.
71.5
N.A.
57.5
59.3
N.A.
N.A.
P-Site Identity:
100
N.A.
0
6.6
N.A.
40
26.6
N.A.
13.3
13.3
N.A.
0
N.A.
0
0
N.A.
N.A.
P-Site Similarity:
100
N.A.
20
20
N.A.
60
60
N.A.
33.3
60
N.A.
13.3
N.A.
13.3
20
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
31.6
26.6
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
46.2
44.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
6.6
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
34
9
9
17
17
0
0
0
0
17
0
9
0
0
% A
% Cys:
9
9
0
0
9
17
0
0
0
0
0
0
0
0
0
% C
% Asp:
9
0
0
0
9
0
0
17
9
9
9
9
0
0
0
% D
% Glu:
9
9
0
34
9
9
9
0
0
9
0
17
9
9
0
% E
% Phe:
0
0
0
9
0
9
0
9
9
0
9
0
0
17
9
% F
% Gly:
0
0
17
9
0
9
0
9
0
9
0
17
0
9
9
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
9
0
% H
% Ile:
0
0
9
17
0
17
0
9
0
9
0
0
9
9
9
% I
% Lys:
0
0
0
9
0
0
9
9
9
0
9
9
0
9
9
% K
% Leu:
25
25
0
0
0
0
17
9
9
0
9
0
9
17
9
% L
% Met:
9
0
0
0
0
0
0
0
9
0
0
0
0
9
0
% M
% Asn:
0
17
0
0
25
0
0
9
34
9
9
0
17
0
9
% N
% Pro:
0
0
9
0
9
0
9
9
0
17
9
9
9
0
9
% P
% Gln:
0
0
0
9
0
0
0
0
0
0
0
17
0
0
9
% Q
% Arg:
0
0
17
0
9
0
0
0
0
17
0
9
0
0
0
% R
% Ser:
0
0
17
9
9
9
25
0
9
9
0
9
25
9
17
% S
% Thr:
9
0
17
0
9
9
17
25
0
9
9
0
0
9
9
% T
% Val:
25
9
9
0
0
9
17
0
9
0
25
9
17
0
9
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
9
9
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _