KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ATP7B
All Species:
2.42
Human Site:
T448
Identified Species:
4.85
UniProt:
P35670
Number Species:
11
Phosphosite Substitution
Charge Score:
0.27
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P35670
NP_000044.2
1465
157263
T448
A
G
N
S
M
V
Q
T
T
D
G
T
P
T
S
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001103242
1333
143814
I435
P
L
E
I
A
Q
L
I
Q
D
L
G
F
E
A
Dog
Lupus familis
XP_860306
1504
164598
E465
I
I
G
Q
T
S
S
E
M
P
L
L
T
S
T
Cat
Felis silvestris
Mouse
Mus musculus
Q64446
1462
157279
T450
S
G
N
S
V
P
Q
T
M
G
D
I
A
G
S
Rat
Rattus norvegicus
Q64535
1451
155972
D444
S
V
P
Q
A
V
G
D
S
P
G
S
V
Q
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507266
1609
174606
N478
S
H
D
Q
G
A
L
N
S
T
G
Q
P
L
T
Chicken
Gallus gallus
XP_417073
1516
163625
V512
K
G
L
E
V
V
Q
V
S
E
N
T
S
V
G
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001036185
1482
159963
P434
P
E
T
N
S
L
V
P
S
V
V
K
S
P
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_572756
1254
136064
N361
G
R
D
K
M
A
H
N
Y
L
E
H
K
E
E
Honey Bee
Apis mellifera
XP_395837
1274
139224
C382
G
I
R
D
I
I
E
C
I
N
K
L
G
F
T
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9SH30
995
108318
E103
Y
P
N
S
V
D
V
E
T
I
R
E
T
I
E
Baker's Yeast
Sacchar. cerevisiae
P38995
1004
109810
V112
I
E
G
V
E
S
V
V
V
S
L
V
T
E
E
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
88
56.5
N.A.
82.8
82.3
N.A.
49.7
68
N.A.
56.3
N.A.
40.8
42.5
N.A.
N.A.
Protein Similarity:
100
N.A.
89.3
72.5
N.A.
89.9
88.8
N.A.
65.1
80.9
N.A.
71.5
N.A.
57.5
59.3
N.A.
N.A.
P-Site Identity:
100
N.A.
6.6
0
N.A.
40
13.3
N.A.
13.3
26.6
N.A.
6.6
N.A.
6.6
0
N.A.
N.A.
P-Site Similarity:
100
N.A.
13.3
13.3
N.A.
53.3
40
N.A.
40
46.6
N.A.
26.6
N.A.
13.3
33.3
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
31.6
26.6
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
46.2
44.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
20
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
0
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
0
0
0
17
17
0
0
0
0
0
0
9
0
9
% A
% Cys:
0
0
0
0
0
0
0
9
0
0
0
0
0
0
0
% C
% Asp:
0
0
17
9
0
9
0
9
0
17
9
0
0
0
0
% D
% Glu:
0
17
9
9
9
0
9
17
0
9
9
9
0
25
25
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
9
9
0
% F
% Gly:
17
25
17
0
9
0
9
0
0
9
25
9
9
9
9
% G
% His:
0
9
0
0
0
0
9
0
0
0
0
9
0
0
0
% H
% Ile:
17
17
0
9
9
9
0
9
9
9
0
9
0
9
0
% I
% Lys:
9
0
0
9
0
0
0
0
0
0
9
9
9
0
0
% K
% Leu:
0
9
9
0
0
9
17
0
0
9
25
17
0
9
0
% L
% Met:
0
0
0
0
17
0
0
0
17
0
0
0
0
0
0
% M
% Asn:
0
0
25
9
0
0
0
17
0
9
9
0
0
0
9
% N
% Pro:
17
9
9
0
0
9
0
9
0
17
0
0
17
9
0
% P
% Gln:
0
0
0
25
0
9
25
0
9
0
0
9
0
9
0
% Q
% Arg:
0
9
9
0
0
0
0
0
0
0
9
0
0
0
0
% R
% Ser:
25
0
0
25
9
17
9
0
34
9
0
9
17
9
25
% S
% Thr:
0
0
9
0
9
0
0
17
17
9
0
17
25
9
25
% T
% Val:
0
9
0
9
25
25
25
17
9
9
9
9
9
9
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
9
0
0
0
0
0
0
0
9
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _