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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ATP7B All Species: 22.12
Human Site: T865 Identified Species: 44.24
UniProt: P35670 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P35670 NP_000044.2 1465 157263 T865 T G E A M P V T K K P G S T V
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001103242 1333 143814 R787 P I Q Q L A D R F S G Y F V P
Dog Lupus familis XP_860306 1504 164598 A886 T G E A M P V A K K S G S T V
Cat Felis silvestris
Mouse Mus musculus Q64446 1462 157279 T867 T G E A M P V T K K P G S I V
Rat Rattus norvegicus Q64535 1451 155972 T858 T G E A M P V T K K P G S I V
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001507266 1609 174606 T992 T G E A M P V T K K P G S T V
Chicken Gallus gallus XP_417073 1516 163625 T925 T G E A M P V T K K P G S T V
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_001036185 1482 159963 T867 T G E A M P V T K K P G S T V
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_572756 1254 136064 P711 C A L G L A T P T A V M V A T
Honey Bee Apis mellifera XP_395837 1274 139224 I732 G M N R E E I I F Q Y A F R S
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9SH30 995 108318 E453 I L L S L D K E G N V T G E E
Baker's Yeast Sacchar. cerevisiae P38995 1004 109810 L462 E S E I D E S L M T G E S I L
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 88 56.5 N.A. 82.8 82.3 N.A. 49.7 68 N.A. 56.3 N.A. 40.8 42.5 N.A. N.A.
Protein Similarity: 100 N.A. 89.3 72.5 N.A. 89.9 88.8 N.A. 65.1 80.9 N.A. 71.5 N.A. 57.5 59.3 N.A. N.A.
P-Site Identity: 100 N.A. 0 86.6 N.A. 93.3 93.3 N.A. 100 100 N.A. 100 N.A. 0 0 N.A. N.A.
P-Site Similarity: 100 N.A. 13.3 86.6 N.A. 93.3 93.3 N.A. 100 100 N.A. 100 N.A. 6.6 13.3 N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. 31.6 26.6 N.A.
Protein Similarity: N.A. N.A. N.A. 46.2 44.1 N.A.
P-Site Identity: N.A. N.A. N.A. 0 13.3 N.A.
P-Site Similarity: N.A. N.A. N.A. 13.3 20 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 9 0 59 0 17 0 9 0 9 0 9 0 9 0 % A
% Cys: 9 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 9 9 9 0 0 0 0 0 0 0 0 % D
% Glu: 9 0 67 0 9 17 0 9 0 0 0 9 0 9 9 % E
% Phe: 0 0 0 0 0 0 0 0 17 0 0 0 17 0 0 % F
% Gly: 9 59 0 9 0 0 0 0 9 0 17 59 9 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 9 9 0 9 0 0 9 9 0 0 0 0 0 25 0 % I
% Lys: 0 0 0 0 0 0 9 0 59 59 0 0 0 0 0 % K
% Leu: 0 9 17 0 25 0 0 9 0 0 0 0 0 0 9 % L
% Met: 0 9 0 0 59 0 0 0 9 0 0 9 0 0 0 % M
% Asn: 0 0 9 0 0 0 0 0 0 9 0 0 0 0 0 % N
% Pro: 9 0 0 0 0 59 0 9 0 0 50 0 0 0 9 % P
% Gln: 0 0 9 9 0 0 0 0 0 9 0 0 0 0 0 % Q
% Arg: 0 0 0 9 0 0 0 9 0 0 0 0 0 9 0 % R
% Ser: 0 9 0 9 0 0 9 0 0 9 9 0 67 0 9 % S
% Thr: 59 0 0 0 0 0 9 50 9 9 0 9 0 42 9 % T
% Val: 0 0 0 0 0 0 59 0 0 0 17 0 9 9 59 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 9 9 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _