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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ATP7B
All Species:
21.82
Human Site:
Y953
Identified Species:
43.64
UniProt:
P35670
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P35670
NP_000044.2
1465
157263
Y953
D
F
G
V
V
Q
R
Y
F
P
N
P
N
K
H
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001103242
1333
143814
Q872
V
G
T
G
V
A
A
Q
N
G
I
L
I
K
G
Dog
Lupus familis
XP_860306
1504
164598
Y974
N
F
E
I
V
E
T
Y
F
P
G
Y
N
R
S
Cat
Felis silvestris
Mouse
Mus musculus
Q64446
1462
157279
Y955
D
F
G
V
V
Q
K
Y
F
P
S
P
S
K
H
Rat
Rattus norvegicus
Q64535
1451
155972
Y946
D
F
G
I
V
Q
K
Y
F
P
S
P
S
K
H
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507266
1609
174606
Y1080
N
F
E
I
V
E
N
Y
F
P
G
Y
N
T
S
Chicken
Gallus gallus
XP_417073
1516
163625
Y1013
N
F
D
I
I
Q
K
Y
F
P
N
Q
N
K
H
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001036185
1482
159963
Y955
N
F
S
L
V
Q
T
Y
F
P
G
Y
D
K
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_572756
1254
136064
F797
I
A
S
A
I
V
H
F
A
K
D
M
L
N
V
Honey Bee
Apis mellifera
XP_395837
1274
139224
S817
F
V
N
E
K
L
C
S
L
A
K
F
L
V
I
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9SH30
995
108318
L538
R
V
G
S
E
S
A
L
A
Q
I
V
R
L
V
Baker's Yeast
Sacchar. cerevisiae
P38995
1004
109810
F547
L
T
F
F
I
W
C
F
I
L
N
I
S
A
N
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
88
56.5
N.A.
82.8
82.3
N.A.
49.7
68
N.A.
56.3
N.A.
40.8
42.5
N.A.
N.A.
Protein Similarity:
100
N.A.
89.3
72.5
N.A.
89.9
88.8
N.A.
65.1
80.9
N.A.
71.5
N.A.
57.5
59.3
N.A.
N.A.
P-Site Identity:
100
N.A.
13.3
40
N.A.
80
73.3
N.A.
40
60
N.A.
46.6
N.A.
0
0
N.A.
N.A.
P-Site Similarity:
100
N.A.
13.3
66.6
N.A.
100
100
N.A.
60
86.6
N.A.
66.6
N.A.
20
0
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
31.6
26.6
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
46.2
44.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
6.6
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
9
0
9
0
9
17
0
17
9
0
0
0
9
0
% A
% Cys:
0
0
0
0
0
0
17
0
0
0
0
0
0
0
0
% C
% Asp:
25
0
9
0
0
0
0
0
0
0
9
0
9
0
0
% D
% Glu:
0
0
17
9
9
17
0
0
0
0
0
0
0
0
0
% E
% Phe:
9
59
9
9
0
0
0
17
59
0
0
9
0
0
0
% F
% Gly:
0
9
34
9
0
0
0
0
0
9
25
0
0
0
9
% G
% His:
0
0
0
0
0
0
9
0
0
0
0
0
0
0
34
% H
% Ile:
9
0
0
34
25
0
0
0
9
0
17
9
9
0
9
% I
% Lys:
0
0
0
0
9
0
25
0
0
9
9
0
0
50
0
% K
% Leu:
9
0
0
9
0
9
0
9
9
9
0
9
17
9
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
9
0
0
0
% M
% Asn:
34
0
9
0
0
0
9
0
9
0
25
0
34
9
9
% N
% Pro:
0
0
0
0
0
0
0
0
0
59
0
25
0
0
0
% P
% Gln:
0
0
0
0
0
42
0
9
0
9
0
9
0
0
0
% Q
% Arg:
9
0
0
0
0
0
9
0
0
0
0
0
9
9
0
% R
% Ser:
0
0
17
9
0
9
0
9
0
0
17
0
25
0
25
% S
% Thr:
0
9
9
0
0
0
17
0
0
0
0
0
0
9
0
% T
% Val:
9
17
0
17
59
9
0
0
0
0
0
9
0
9
17
% V
% Trp:
0
0
0
0
0
9
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
59
0
0
0
25
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _