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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SOX18 All Species: 9.09
Human Site: S57 Identified Species: 22.22
UniProt: P35713 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P35713 NP_060889.1 384 40891 S57 S P P S P Q R S P P R S P E P
Chimpanzee Pan troglodytes Q9BG89 509 56105 V77 P V C I R E A V S Q V L K G Y
Rhesus Macaque Macaca mulatta XP_001083465 384 40895 S57 S P P S P Q R S P P R S P E P
Dog Lupus familis XP_543109 209 21522
Cat Felis silvestris
Mouse Mus musculus P43680 377 40880 S54 S P S S L P R S P P R S P E S
Rat Rattus norvegicus O55170 466 50021 V76 P V C I R E A V S Q V L S G Y
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus P48434 494 54924 V78 P V C I R E A V S Q V L K G Y
Frog Xenopus laevis Q90ZH8 363 40927 G53 P A P S P K P G Y G F S T C E
Zebra Danio Brachydanio rerio Q6EJB7 300 33398 S46 M N A F M V W S R G Q R R K M
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P40657 784 84853 Y187 L C A P N C G Y L E R H K P L
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 26.9 98.6 47.1 N.A. 86.4 27.2 N.A. N.A. 26.5 48.1 23.4 N.A. 22.9 N.A. N.A. N.A.
Protein Similarity: 100 37.9 98.6 50 N.A. 88.8 39 N.A. N.A. 37.4 59.1 39.8 N.A. 31.2 N.A. N.A. N.A.
P-Site Identity: 100 0 100 0 N.A. 73.3 0 N.A. N.A. 0 26.6 6.6 N.A. 6.6 N.A. N.A. N.A.
P-Site Similarity: 100 6.6 100 0 N.A. 73.3 6.6 N.A. N.A. 6.6 33.3 20 N.A. 6.6 N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 10 20 0 0 0 30 0 0 0 0 0 0 0 0 % A
% Cys: 0 10 30 0 0 10 0 0 0 0 0 0 0 10 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 30 0 0 0 10 0 0 0 30 10 % E
% Phe: 0 0 0 10 0 0 0 0 0 0 10 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 10 10 0 20 0 0 0 30 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 10 0 0 0 % H
% Ile: 0 0 0 30 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 10 0 0 0 0 0 0 30 10 0 % K
% Leu: 10 0 0 0 10 0 0 0 10 0 0 30 0 0 10 % L
% Met: 10 0 0 0 10 0 0 0 0 0 0 0 0 0 10 % M
% Asn: 0 10 0 0 10 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 40 30 30 10 30 10 10 0 30 30 0 0 30 10 20 % P
% Gln: 0 0 0 0 0 20 0 0 0 30 10 0 0 0 0 % Q
% Arg: 0 0 0 0 30 0 30 0 10 0 40 10 10 0 0 % R
% Ser: 30 0 10 40 0 0 0 40 30 0 0 40 10 0 10 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 0 0 10 0 0 % T
% Val: 0 30 0 0 0 10 0 30 0 0 30 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 10 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 10 10 0 0 0 0 0 30 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _