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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GLRX
All Species:
38.18
Human Site:
S84
Identified Species:
70
UniProt:
P35754
Number Species:
12
Phosphosite Substitution
Charge Score:
0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P35754
NP_001112362.1
106
11776
S84
K
D
C
I
G
G
C
S
D
L
V
S
L
Q
Q
Chimpanzee
Pan troglodytes
XP_001144419
106
11895
S84
K
D
C
I
G
G
C
S
D
L
V
S
M
Q
Q
Rhesus Macaque
Macaca mulatta
XP_001093482
106
11729
S84
K
D
C
I
G
G
C
S
D
L
V
S
M
Q
Q
Dog
Lupus familis
XP_851559
106
11466
S84
R
D
C
I
G
G
C
S
D
L
I
E
M
N
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q9QUH0
107
11852
S84
K
D
C
I
G
G
C
S
D
L
I
S
M
Q
Q
Rat
Rattus norvegicus
Q9ESH6
107
11860
S84
K
D
C
I
G
G
C
S
D
L
L
S
M
Q
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
P79764
101
11379
S81
T
K
C
I
G
G
F
S
D
L
Q
K
M
E
Q
Frog
Xenopus laevis
NP_001083654
107
11910
S84
E
K
C
I
G
G
C
S
D
L
V
P
L
E
N
Zebra Danio
Brachydanio rerio
NP_001005942
105
11319
S83
E
D
C
V
G
G
G
S
D
V
E
G
L
D
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
NP_490812
105
11279
D84
G
K
F
F
G
G
G
D
D
T
A
A
G
A
K
Sea Urchin
Strong. purpuratus
XP_787379
103
11254
S82
G
K
C
I
G
G
G
S
E
T
K
A
L
Q
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9FNE2
111
11738
D81
G
N
H
I
G
G
C
D
A
T
S
N
L
H
K
Baker's Yeast
Sacchar. cerevisiae
P17695
143
15843
S123
G
K
H
I
G
G
N
S
D
L
E
T
L
K
K
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
91.5
98.1
73.5
N.A.
88.7
87.8
N.A.
N.A.
49
49.5
56.5
N.A.
N.A.
N.A.
44.3
50
Protein Similarity:
100
96.2
99
86.7
N.A.
95.3
93.4
N.A.
N.A.
63.2
68.2
70.7
N.A.
N.A.
N.A.
61.3
68.8
P-Site Identity:
100
93.3
93.3
66.6
N.A.
86.6
86.6
N.A.
N.A.
53.3
66.6
46.6
N.A.
N.A.
N.A.
20
46.6
P-Site Similarity:
100
100
100
86.6
N.A.
100
100
N.A.
N.A.
66.6
80
73.3
N.A.
N.A.
N.A.
33.3
66.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
37.8
25.8
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
52.2
45.4
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
33.3
46.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
53.3
66.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
8
0
8
16
0
8
0
% A
% Cys:
0
0
77
0
0
0
62
0
0
0
0
0
0
0
0
% C
% Asp:
0
54
0
0
0
0
0
16
85
0
0
0
0
8
0
% D
% Glu:
16
0
0
0
0
0
0
0
8
0
16
8
0
16
8
% E
% Phe:
0
0
8
8
0
0
8
0
0
0
0
0
0
0
0
% F
% Gly:
31
0
0
0
100
100
24
0
0
0
0
8
8
0
0
% G
% His:
0
0
16
0
0
0
0
0
0
0
0
0
0
8
0
% H
% Ile:
0
0
0
85
0
0
0
0
0
0
16
0
0
0
0
% I
% Lys:
39
39
0
0
0
0
0
0
0
0
8
8
0
8
24
% K
% Leu:
0
0
0
0
0
0
0
0
0
70
8
0
47
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
47
0
0
% M
% Asn:
0
8
0
0
0
0
8
0
0
0
0
8
0
8
8
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
8
0
0
47
54
% Q
% Arg:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% R
% Ser:
0
0
0
0
0
0
0
85
0
0
8
39
0
0
0
% S
% Thr:
8
0
0
0
0
0
0
0
0
24
0
8
0
0
0
% T
% Val:
0
0
0
8
0
0
0
0
0
8
31
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _