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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GLRX
All Species:
24.85
Human Site:
T49
Identified Species:
45.56
UniProt:
P35754
Number Species:
12
Phosphosite Substitution
Charge Score:
0.33
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P35754
NP_001112362.1
106
11776
T49
L
L
E
F
V
D
I
T
A
T
N
H
T
N
E
Chimpanzee
Pan troglodytes
XP_001144419
106
11895
T49
L
L
E
F
V
D
I
T
A
S
N
H
T
N
K
Rhesus Macaque
Macaca mulatta
XP_001093482
106
11729
T49
L
L
E
F
V
D
I
T
A
T
N
H
T
N
E
Dog
Lupus familis
XP_851559
106
11466
T49
A
L
E
F
V
D
I
T
A
A
G
D
T
S
S
Cat
Felis silvestris
Mouse
Mus musculus
Q9QUH0
107
11852
T49
L
L
E
F
V
D
I
T
A
T
N
N
T
S
A
Rat
Rattus norvegicus
Q9ESH6
107
11860
T49
L
L
E
F
V
D
I
T
A
T
N
N
T
N
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
P79764
101
11379
V46
L
P
G
C
L
E
V
V
D
I
T
G
M
D
D
Frog
Xenopus laevis
NP_001083654
107
11910
S49
H
L
E
I
I
D
I
S
K
L
D
F
M
S
S
Zebra Danio
Brachydanio rerio
NP_001005942
105
11319
S48
H
F
E
L
I
D
I
S
A
R
A
D
M
G
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
NP_490812
105
11279
D49
A
L
Q
W
I
E
I
D
E
R
K
D
C
N
E
Sea Urchin
Strong. purpuratus
XP_787379
103
11254
E47
D
Y
K
V
V
E
L
E
N
H
N
M
C
A
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9FNE2
111
11738
D46
K
F
K
A
V
E
L
D
T
E
S
D
G
S
Q
Baker's Yeast
Sacchar. cerevisiae
P17695
143
15843
D88
K
A
L
V
L
E
L
D
E
M
S
N
G
S
E
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
91.5
98.1
73.5
N.A.
88.7
87.8
N.A.
N.A.
49
49.5
56.5
N.A.
N.A.
N.A.
44.3
50
Protein Similarity:
100
96.2
99
86.7
N.A.
95.3
93.4
N.A.
N.A.
63.2
68.2
70.7
N.A.
N.A.
N.A.
61.3
68.8
P-Site Identity:
100
86.6
100
60
N.A.
80
86.6
N.A.
N.A.
6.6
26.6
26.6
N.A.
N.A.
N.A.
26.6
20
P-Site Similarity:
100
100
100
66.6
N.A.
93.3
93.3
N.A.
N.A.
40
53.3
40
N.A.
N.A.
N.A.
53.3
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
37.8
25.8
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
52.2
45.4
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
46.6
46.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
16
8
0
8
0
0
0
0
54
8
8
0
0
8
16
% A
% Cys:
0
0
0
8
0
0
0
0
0
0
0
0
16
0
0
% C
% Asp:
8
0
0
0
0
62
0
24
8
0
8
31
0
8
8
% D
% Glu:
0
0
62
0
0
39
0
8
16
8
0
0
0
0
39
% E
% Phe:
0
16
0
47
0
0
0
0
0
0
0
8
0
0
0
% F
% Gly:
0
0
8
0
0
0
0
0
0
0
8
8
16
8
0
% G
% His:
16
0
0
0
0
0
0
0
0
8
0
24
0
0
0
% H
% Ile:
0
0
0
8
24
0
70
0
0
8
0
0
0
0
0
% I
% Lys:
16
0
16
0
0
0
0
0
8
0
8
0
0
0
8
% K
% Leu:
47
62
8
8
16
0
24
0
0
8
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
8
0
8
24
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
8
0
47
24
0
39
0
% N
% Pro:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
8
% Q
% Arg:
0
0
0
0
0
0
0
0
0
16
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
16
0
8
16
0
0
39
24
% S
% Thr:
0
0
0
0
0
0
0
47
8
31
8
0
47
0
0
% T
% Val:
0
0
0
16
62
0
8
8
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _