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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CHKA
All Species:
14.55
Human Site:
S225
Identified Species:
35.56
UniProt:
P35790
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P35790
NP_001268.2
457
52249
S225
E
L
S
L
P
D
I
S
A
E
I
A
E
K
M
Chimpanzee
Pan troglodytes
XP_508602
473
54843
S240
E
L
S
L
P
D
I
S
A
E
I
A
E
K
M
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_533210
373
43630
K155
M
A
T
F
H
G
M
K
M
P
F
N
K
E
P
Cat
Felis silvestris
Mouse
Mus musculus
O54804
453
51982
S221
E
L
R
L
P
D
I
S
A
E
I
A
E
K
M
Rat
Rattus norvegicus
Q01134
453
51806
S221
E
L
C
L
P
D
I
S
A
E
I
A
E
K
M
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001520038
436
47973
N212
Q
G
G
G
V
G
S
N
V
H
G
R
S
P
I
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001038330
400
46559
M183
A
R
F
H
G
M
R
M
P
F
N
K
E
P
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P54352
518
59544
S260
H
T
Y
G
L
A
P
S
L
Y
A
T
F
K
N
Honey Bee
Apis mellifera
XP_624492
379
44310
T162
E
P
T
W
L
W
D
T
M
A
K
W
L
D
T
Nematode Worm
Caenorhab. elegans
P46558
371
42767
V153
K
K
R
R
C
F
Q
V
M
R
E
S
L
K
E
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
86.2
N.A.
71.9
N.A.
88.1
89.5
N.A.
32.1
N.A.
N.A.
59.2
N.A.
20
39.1
21.6
N.A.
Protein Similarity:
100
87.9
N.A.
75.9
N.A.
94.7
94.7
N.A.
44.6
N.A.
N.A.
72.4
N.A.
38.2
54.2
37.4
N.A.
P-Site Identity:
100
100
N.A.
0
N.A.
93.3
93.3
N.A.
0
N.A.
N.A.
6.6
N.A.
13.3
6.6
6.6
N.A.
P-Site Similarity:
100
100
N.A.
26.6
N.A.
93.3
93.3
N.A.
20
N.A.
N.A.
6.6
N.A.
13.3
20
20
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
10
0
0
0
10
0
0
40
10
10
40
0
0
0
% A
% Cys:
0
0
10
0
10
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
40
10
0
0
0
0
0
0
10
0
% D
% Glu:
50
0
0
0
0
0
0
0
0
40
10
0
50
10
10
% E
% Phe:
0
0
10
10
0
10
0
0
0
10
10
0
10
0
0
% F
% Gly:
0
10
10
20
10
20
0
0
0
0
10
0
0
0
0
% G
% His:
10
0
0
10
10
0
0
0
0
10
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
40
0
0
0
40
0
0
0
10
% I
% Lys:
10
10
0
0
0
0
0
10
0
0
10
10
10
60
10
% K
% Leu:
0
40
0
40
20
0
0
0
10
0
0
0
20
0
0
% L
% Met:
10
0
0
0
0
10
10
10
30
0
0
0
0
0
40
% M
% Asn:
0
0
0
0
0
0
0
10
0
0
10
10
0
0
10
% N
% Pro:
0
10
0
0
40
0
10
0
10
10
0
0
0
20
10
% P
% Gln:
10
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% Q
% Arg:
0
10
20
10
0
0
10
0
0
10
0
10
0
0
0
% R
% Ser:
0
0
20
0
0
0
10
50
0
0
0
10
10
0
0
% S
% Thr:
0
10
20
0
0
0
0
10
0
0
0
10
0
0
10
% T
% Val:
0
0
0
0
10
0
0
10
10
0
0
0
0
0
0
% V
% Trp:
0
0
0
10
0
10
0
0
0
0
0
10
0
0
0
% W
% Tyr:
0
0
10
0
0
0
0
0
0
10
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _