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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CHKA All Species: 13.64
Human Site: S291 Identified Species: 33.33
UniProt: P35790 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P35790 NP_001268.2 457 52249 S291 L E L E N L R S L L E S T P S
Chimpanzee Pan troglodytes XP_508602 473 54843 S306 L E L E N L R S L L E S T P S
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_533210 373 43630 C219 T P S P V V F C H N D C Q E G
Cat Felis silvestris
Mouse Mus musculus O54804 453 51982 S287 L E L E N L R S L L Q Y T R S
Rat Rattus norvegicus Q01134 453 51806 S287 L E L E N L R S L L Q Y T R S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001520038 436 47973 P275 R E S E D V A P N N A G S A W
Chicken Gallus gallus
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_001038330 400 46559 C246 T P S P V V F C H N D L Q E G
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P54352 518 59544 T323 M P M I W K K T Q S F L D L V
Honey Bee Apis mellifera XP_624492 379 44310 N225 H N D M Q E G N I L L R Q N T
Nematode Worm Caenorhab. elegans P46558 371 42767 L216 V V F C H N D L A S S N I L E
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 86.2 N.A. 71.9 N.A. 88.1 89.5 N.A. 32.1 N.A. N.A. 59.2 N.A. 20 39.1 21.6 N.A.
Protein Similarity: 100 87.9 N.A. 75.9 N.A. 94.7 94.7 N.A. 44.6 N.A. N.A. 72.4 N.A. 38.2 54.2 37.4 N.A.
P-Site Identity: 100 100 N.A. 0 N.A. 80 80 N.A. 13.3 N.A. N.A. 0 N.A. 0 6.6 0 N.A.
P-Site Similarity: 100 100 N.A. 13.3 N.A. 86.6 86.6 N.A. 33.3 N.A. N.A. 13.3 N.A. 26.6 26.6 20 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 10 0 10 0 10 0 0 10 0 % A
% Cys: 0 0 0 10 0 0 0 20 0 0 0 10 0 0 0 % C
% Asp: 0 0 10 0 10 0 10 0 0 0 20 0 10 0 0 % D
% Glu: 0 50 0 50 0 10 0 0 0 0 20 0 0 20 10 % E
% Phe: 0 0 10 0 0 0 20 0 0 0 10 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 10 0 0 0 0 10 0 0 20 % G
% His: 10 0 0 0 10 0 0 0 20 0 0 0 0 0 0 % H
% Ile: 0 0 0 10 0 0 0 0 10 0 0 0 10 0 0 % I
% Lys: 0 0 0 0 0 10 10 0 0 0 0 0 0 0 0 % K
% Leu: 40 0 40 0 0 40 0 10 40 50 10 20 0 20 0 % L
% Met: 10 0 10 10 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 10 0 0 40 10 0 10 10 30 0 10 0 10 0 % N
% Pro: 0 30 0 20 0 0 0 10 0 0 0 0 0 20 0 % P
% Gln: 0 0 0 0 10 0 0 0 10 0 20 0 30 0 0 % Q
% Arg: 10 0 0 0 0 0 40 0 0 0 0 10 0 20 0 % R
% Ser: 0 0 30 0 0 0 0 40 0 20 10 20 10 0 40 % S
% Thr: 20 0 0 0 0 0 0 10 0 0 0 0 40 0 10 % T
% Val: 10 10 0 0 20 30 0 0 0 0 0 0 0 0 10 % V
% Trp: 0 0 0 0 10 0 0 0 0 0 0 0 0 0 10 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 20 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _