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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PPM1A
All Species:
39.7
Human Site:
S125
Identified Species:
72.78
UniProt:
P35813
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P35813
NP_066283.1
382
42448
S125
K
K
H
G
A
D
R
S
G
S
T
A
V
G
V
Chimpanzee
Pan troglodytes
XP_001167412
430
48336
S173
K
K
H
G
A
D
R
S
G
S
T
A
V
G
V
Rhesus Macaque
Macaca mulatta
XP_001095896
354
39114
R113
L
E
I
D
E
H
M
R
V
M
S
E
K
K
H
Dog
Lupus familis
XP_537467
382
42427
S125
K
K
H
G
A
D
R
S
G
S
T
A
V
G
V
Cat
Felis silvestris
Mouse
Mus musculus
P49443
382
42414
S125
K
K
H
G
A
D
R
S
G
S
T
A
V
G
V
Rat
Rattus norvegicus
P20650
382
42398
S125
K
K
H
G
A
D
R
S
G
S
T
A
V
G
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512797
382
42443
S125
K
K
H
G
A
D
R
S
G
S
T
A
V
G
V
Chicken
Gallus gallus
XP_421422
382
42461
S125
K
K
H
G
A
D
R
S
G
S
T
A
V
G
V
Frog
Xenopus laevis
NP_001080366
383
42664
S125
K
K
H
G
A
D
R
S
G
S
T
A
V
G
V
Zebra Danio
Brachydanio rerio
NP_571504
384
42071
S132
K
H
G
G
A
D
R
S
G
S
T
A
V
G
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P49596
356
39046
S115
E
E
T
K
D
D
V
S
G
T
T
A
V
V
V
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
O81716
355
39336
S122
G
D
K
M
N
K
F
S
G
M
I
E
G
F
I
Baker's Yeast
Sacchar. cerevisiae
P34221
468
51372
C120
L
K
D
D
H
S
G
C
T
A
T
V
I
L
V
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
88.8
92.6
99.4
N.A.
98.1
98.9
N.A.
93.4
93.9
90.5
83.5
N.A.
N.A.
N.A.
36.6
N.A.
Protein Similarity:
100
88.8
92.6
99.7
N.A.
98.9
99.2
N.A.
98.1
98.4
96
92.1
N.A.
N.A.
N.A.
51.5
N.A.
P-Site Identity:
100
100
0
100
N.A.
100
100
N.A.
100
100
100
86.6
N.A.
N.A.
N.A.
46.6
N.A.
P-Site Similarity:
100
100
13.3
100
N.A.
100
100
N.A.
100
100
100
86.6
N.A.
N.A.
N.A.
66.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
22.5
27.9
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
40.5
44.8
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
20
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
70
0
0
0
0
8
0
77
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% C
% Asp:
0
8
8
16
8
77
0
0
0
0
0
0
0
0
0
% D
% Glu:
8
16
0
0
8
0
0
0
0
0
0
16
0
0
0
% E
% Phe:
0
0
0
0
0
0
8
0
0
0
0
0
0
8
0
% F
% Gly:
8
0
8
70
0
0
8
0
85
0
0
0
8
70
0
% G
% His:
0
8
62
0
8
8
0
0
0
0
0
0
0
0
8
% H
% Ile:
0
0
8
0
0
0
0
0
0
0
8
0
8
0
8
% I
% Lys:
70
70
8
8
0
8
0
0
0
0
0
0
8
8
0
% K
% Leu:
16
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% L
% Met:
0
0
0
8
0
0
8
0
0
16
0
0
0
0
0
% M
% Asn:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
70
8
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
8
0
85
0
70
8
0
0
0
0
% S
% Thr:
0
0
8
0
0
0
0
0
8
8
85
0
0
0
0
% T
% Val:
0
0
0
0
0
0
8
0
8
0
0
8
77
8
85
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _