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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PPM1A
All Species:
32.73
Human Site:
S375
Identified Species:
60
UniProt:
P35813
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P35813
NP_066283.1
382
42448
S375
Y
K
N
D
D
T
D
S
T
S
T
D
D
M
W
Chimpanzee
Pan troglodytes
XP_001167412
430
48336
S423
Y
K
N
D
D
T
D
S
T
S
T
D
D
M
W
Rhesus Macaque
Macaca mulatta
XP_001095896
354
39114
S344
L
A
S
E
N
I
P
S
L
P
P
G
G
E
L
Dog
Lupus familis
XP_537467
382
42427
S375
Y
K
N
D
D
T
D
S
T
S
T
D
D
M
W
Cat
Felis silvestris
Mouse
Mus musculus
P49443
382
42414
S375
Y
K
N
D
D
T
D
S
A
S
T
D
D
M
W
Rat
Rattus norvegicus
P20650
382
42398
S375
Y
K
N
D
D
T
D
S
A
S
T
D
D
M
W
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512797
382
42443
S375
Y
R
N
D
D
T
D
S
A
S
T
D
D
M
W
Chicken
Gallus gallus
XP_421422
382
42461
S375
Y
R
N
D
D
T
D
S
A
S
T
D
D
M
W
Frog
Xenopus laevis
NP_001080366
383
42664
S376
Y
R
N
D
D
T
D
S
A
S
T
D
D
M
W
Zebra Danio
Brachydanio rerio
NP_571504
384
42071
Y376
V
Y
N
K
L
N
P
Y
R
N
E
D
T
V
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P49596
356
39046
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
O81716
355
39336
Baker's Yeast
Sacchar. cerevisiae
P34221
468
51372
A458
E
N
G
K
N
E
N
A
K
K
G
S
K
I
E
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
88.8
92.6
99.4
N.A.
98.1
98.9
N.A.
93.4
93.9
90.5
83.5
N.A.
N.A.
N.A.
36.6
N.A.
Protein Similarity:
100
88.8
92.6
99.7
N.A.
98.9
99.2
N.A.
98.1
98.4
96
92.1
N.A.
N.A.
N.A.
51.5
N.A.
P-Site Identity:
100
100
6.6
100
N.A.
93.3
93.3
N.A.
86.6
86.6
86.6
13.3
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
100
100
26.6
100
N.A.
93.3
93.3
N.A.
93.3
93.3
93.3
26.6
N.A.
N.A.
N.A.
0
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
22.5
27.9
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
40.5
44.8
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
0
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
0
0
0
0
0
8
39
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
62
62
0
62
0
0
0
0
70
62
0
0
% D
% Glu:
8
0
0
8
0
8
0
0
0
0
8
0
0
8
8
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
8
0
0
0
0
0
0
0
8
8
8
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
8
0
0
0
0
0
0
0
8
0
% I
% Lys:
0
39
0
16
0
0
0
0
8
8
0
0
8
0
0
% K
% Leu:
8
0
0
0
8
0
0
0
8
0
0
0
0
0
16
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
62
0
% M
% Asn:
0
8
70
0
16
8
8
0
0
8
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
16
0
0
8
8
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
24
0
0
0
0
0
0
8
0
0
0
0
0
0
% R
% Ser:
0
0
8
0
0
0
0
70
0
62
0
8
0
0
0
% S
% Thr:
0
0
0
0
0
62
0
0
24
0
62
0
8
0
0
% T
% Val:
8
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
62
% W
% Tyr:
62
8
0
0
0
0
0
8
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _