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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PDE6B
All Species:
8.48
Human Site:
S297
Identified Species:
14.36
UniProt:
P35913
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.15
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P35913
NP_000274.2
854
98336
S297
W
S
V
L
M
G
E
S
Q
P
Y
S
G
P
R
Chimpanzee
Pan troglodytes
XP_518030
860
99527
V299
W
P
V
L
M
G
E
V
P
P
Y
S
G
P
R
Rhesus Macaque
Macaca mulatta
XP_001094732
854
97937
S297
W
P
V
L
M
G
E
S
Q
P
Y
S
G
P
R
Dog
Lupus familis
XP_543934
846
97567
V286
W
P
I
K
L
G
E
V
E
P
Y
K
G
P
K
Cat
Felis silvestris
Mouse
Mus musculus
P23440
856
98483
A297
W
P
V
L
M
G
E
A
Q
P
Y
S
G
P
R
Rat
Rattus norvegicus
Q8VID6
935
104553
Y362
D
E
K
V
M
Q
M
Y
L
P
F
C
G
I
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512709
856
98818
V297
W
P
V
L
M
G
E
V
Q
P
Y
T
G
P
R
Chicken
Gallus gallus
P52731
862
99990
A301
W
P
I
R
L
G
E
A
E
P
Y
K
G
P
K
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_685002
854
98605
Q298
W
P
V
L
M
G
E
Q
P
P
Y
S
G
P
V
Tiger Blowfish
Takifugu rubipres
Q1KKS3
903
102001
T355
N
D
L
F
E
E
Q
T
D
L
E
K
I
V
R
Fruit Fly
Dros. melanogaster
Q9VFI9
1131
125621
Q489
K
I
I
E
K
P
N
Q
P
A
T
R
A
I
K
Honey Bee
Apis mellifera
XP_394107
1016
115998
K428
K
I
V
E
R
P
G
K
S
M
Q
E
S
R
K
Nematode Worm
Caenorhab. elegans
P91119
710
81117
S227
F
L
L
D
V
A
R
S
I
F
H
D
I
V
S
Sea Urchin
Strong. purpuratus
NP_001029121
949
108476
R378
L
R
M
A
E
G
K
R
H
S
I
A
Y
Q
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
71.4
93.9
63.8
N.A.
92.5
24.9
N.A.
86.2
64.5
N.A.
76.1
24.2
23.7
25.6
23.8
32.9
Protein Similarity:
100
82.3
96.7
79.1
N.A.
96.2
44.1
N.A.
92.6
78.8
N.A.
85.1
43.7
41.2
44.6
42.3
53.2
P-Site Identity:
100
80
93.3
46.6
N.A.
86.6
20
N.A.
80
46.6
N.A.
73.3
6.6
0
6.6
6.6
6.6
P-Site Similarity:
100
80
93.3
73.3
N.A.
93.3
33.3
N.A.
86.6
80
N.A.
73.3
26.6
13.3
13.3
33.3
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
8
0
8
0
15
0
8
0
8
8
0
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% C
% Asp:
8
8
0
8
0
0
0
0
8
0
0
8
0
0
0
% D
% Glu:
0
8
0
15
15
8
58
0
15
0
8
8
0
0
0
% E
% Phe:
8
0
0
8
0
0
0
0
0
8
8
0
0
0
0
% F
% Gly:
0
0
0
0
0
65
8
0
0
0
0
0
65
0
0
% G
% His:
0
0
0
0
0
0
0
0
8
0
8
0
0
0
0
% H
% Ile:
0
15
22
0
0
0
0
0
8
0
8
0
15
15
0
% I
% Lys:
15
0
8
8
8
0
8
8
0
0
0
22
0
0
29
% K
% Leu:
8
8
15
43
15
0
0
0
8
8
0
0
0
0
0
% L
% Met:
0
0
8
0
50
0
8
0
0
8
0
0
0
0
0
% M
% Asn:
8
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% N
% Pro:
0
50
0
0
0
15
0
0
22
65
0
0
0
58
0
% P
% Gln:
0
0
0
0
0
8
8
15
29
0
8
0
0
8
0
% Q
% Arg:
0
8
0
8
8
0
8
8
0
0
0
8
0
8
43
% R
% Ser:
0
8
0
0
0
0
0
22
8
8
0
36
8
0
15
% S
% Thr:
0
0
0
0
0
0
0
8
0
0
8
8
0
0
0
% T
% Val:
0
0
50
8
8
0
0
22
0
0
0
0
0
15
8
% V
% Trp:
58
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
8
0
0
58
0
8
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _