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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PDE6B
All Species:
15.15
Human Site:
S694
Identified Species:
25.64
UniProt:
P35913
Number Species:
13
Phosphosite Substitution
Charge Score:
0.38
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P35913
NP_000274.2
854
98336
S694
K
N
Y
Q
D
K
K
S
W
V
E
Y
L
S
L
Chimpanzee
Pan troglodytes
XP_518030
860
99527
E696
K
T
Y
E
S
E
Q
E
W
T
Q
Y
M
M
L
Rhesus Macaque
Macaca mulatta
XP_001094732
854
97937
S693
K
N
Y
E
D
K
K
S
W
V
E
Y
L
S
L
Dog
Lupus familis
XP_543934
846
97567
E684
E
K
M
E
T
E
E
E
A
I
K
Y
V
T
I
Cat
Felis silvestris
Mouse
Mus musculus
P23440
856
98483
S694
K
N
Y
E
D
K
K
S
W
V
E
Y
L
S
L
Rat
Rattus norvegicus
Q8VID6
935
104553
S802
A
Y
D
W
S
I
T
S
H
R
D
V
F
R
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512709
856
98818
S694
K
G
Y
D
D
K
K
S
W
V
E
Y
L
S
L
Chicken
Gallus gallus
P52731
862
99990
E699
E
K
M
E
T
E
E
E
A
I
K
Y
I
S
I
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_685002
854
98605
K695
E
T
Y
E
E
R
K
K
W
I
D
F
M
S
L
Tiger Blowfish
Takifugu rubipres
Q1KKS3
903
102001
T756
E
Y
N
W
N
V
K
T
H
R
D
M
C
R
S
Fruit Fly
Dros. melanogaster
Q9VFI9
1131
125621
E868
E
F
D
W
Q
G
E
E
K
K
D
L
L
C
G
Honey Bee
Apis mellifera
XP_394107
1016
115998
E803
E
F
D
W
Q
S
E
E
K
K
E
L
L
C
G
Nematode Worm
Caenorhab. elegans
P91119
710
81117
L591
S
L
I
K
H
C
I
L
A
T
D
L
A
L
F
Sea Urchin
Strong. purpuratus
NP_001029121
949
108476
E755
E
H
T
W
D
N
E
E
K
K
G
L
L
R
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
71.4
93.9
63.8
N.A.
92.5
24.9
N.A.
86.2
64.5
N.A.
76.1
24.2
23.7
25.6
23.8
32.9
Protein Similarity:
100
82.3
96.7
79.1
N.A.
96.2
44.1
N.A.
92.6
78.8
N.A.
85.1
43.7
41.2
44.6
42.3
53.2
P-Site Identity:
100
33.3
93.3
6.6
N.A.
93.3
6.6
N.A.
86.6
13.3
N.A.
33.3
6.6
6.6
13.3
0
13.3
P-Site Similarity:
100
66.6
100
66.6
N.A.
100
13.3
N.A.
86.6
66.6
N.A.
86.6
33.3
26.6
26.6
13.3
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
0
0
0
0
0
22
0
0
0
8
0
0
% A
% Cys:
0
0
0
0
0
8
0
0
0
0
0
0
8
15
0
% C
% Asp:
0
0
22
8
36
0
0
0
0
0
36
0
0
0
0
% D
% Glu:
50
0
0
43
8
22
36
43
0
0
36
0
0
0
0
% E
% Phe:
0
15
0
0
0
0
0
0
0
0
0
8
8
0
8
% F
% Gly:
0
8
0
0
0
8
0
0
0
0
8
0
0
0
22
% G
% His:
0
8
0
0
8
0
0
0
15
0
0
0
0
0
0
% H
% Ile:
0
0
8
0
0
8
8
0
0
22
0
0
8
0
15
% I
% Lys:
36
15
0
8
0
29
43
8
22
22
15
0
0
0
0
% K
% Leu:
0
8
0
0
0
0
0
8
0
0
0
29
50
8
43
% L
% Met:
0
0
15
0
0
0
0
0
0
0
0
8
15
8
0
% M
% Asn:
0
22
8
0
8
8
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
8
15
0
8
0
0
0
8
0
0
0
0
% Q
% Arg:
0
0
0
0
0
8
0
0
0
15
0
0
0
22
0
% R
% Ser:
8
0
0
0
15
8
0
36
0
0
0
0
0
43
15
% S
% Thr:
0
15
8
0
15
0
8
8
0
15
0
0
0
8
0
% T
% Val:
0
0
0
0
0
8
0
0
0
29
0
8
8
0
0
% V
% Trp:
0
0
0
36
0
0
0
0
43
0
0
0
0
0
0
% W
% Tyr:
0
15
43
0
0
0
0
0
0
0
0
50
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _