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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PDE6B
All Species:
23.27
Human Site:
S848
Identified Species:
39.38
UniProt:
P35913
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P35913
NP_000274.2
854
98336
S848
N
G
G
P
A
P
K
S
S
T
C
C
I
L
_
Chimpanzee
Pan troglodytes
XP_518030
860
99527
S854
S
P
G
G
A
T
T
S
K
S
C
C
I
Q
_
Rhesus Macaque
Macaca mulatta
XP_001094732
854
97937
S848
N
G
G
P
A
P
K
S
S
T
C
C
I
L
_
Dog
Lupus familis
XP_543934
846
97567
S840
G
G
V
D
D
K
K
S
K
T
C
L
M
L
_
Cat
Felis silvestris
Mouse
Mus musculus
P23440
856
98483
S850
N
G
G
P
A
P
K
S
S
T
C
C
I
L
_
Rat
Rattus norvegicus
Q8VID6
935
104553
S926
S
P
V
P
S
S
P
S
P
A
V
A
G
E
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512709
856
98818
S850
N
G
G
P
S
P
Q
S
S
T
C
T
I
L
_
Chicken
Gallus gallus
P52731
862
99990
S856
G
G
G
E
D
G
K
S
K
T
C
I
V
L
_
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_685002
854
98605
Tiger Blowfish
Takifugu rubipres
Q1KKS3
903
102001
T897
V
P
C
C
S
N
N
T
P
P
T
H
V
S
_
Fruit Fly
Dros. melanogaster
Q9VFI9
1131
125621
K1070
S
M
D
G
S
K
P
K
T
S
L
K
L
L
E
Honey Bee
Apis mellifera
XP_394107
1016
115998
S983
K
D
V
R
H
R
L
S
R
P
L
Y
A
R
N
Nematode Worm
Caenorhab. elegans
P91119
710
81117
Sea Urchin
Strong. purpuratus
NP_001029121
949
108476
A937
Q
Q
C
K
E
A
L
A
A
K
K
N
K
S
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
71.4
93.9
63.8
N.A.
92.5
24.9
N.A.
86.2
64.5
N.A.
76.1
24.2
23.7
25.6
23.8
32.9
Protein Similarity:
100
82.3
96.7
79.1
N.A.
96.2
44.1
N.A.
92.6
78.8
N.A.
85.1
43.7
41.2
44.6
42.3
53.2
P-Site Identity:
100
42.8
100
42.8
N.A.
100
13.3
N.A.
78.5
50
N.A.
0
0
6.6
6.6
0
0
P-Site Similarity:
100
57.1
100
50
N.A.
100
26.6
N.A.
92.8
57.1
N.A.
0
21.4
40
6.6
0
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
29
8
0
8
8
8
0
8
8
0
0
% A
% Cys:
0
0
15
8
0
0
0
0
0
0
50
29
0
0
0
% C
% Asp:
0
8
8
8
15
0
0
0
0
0
0
0
0
0
8
% D
% Glu:
0
0
0
8
8
0
0
0
0
0
0
0
0
8
8
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
15
43
43
15
0
8
0
0
0
0
0
0
8
0
0
% G
% His:
0
0
0
0
8
0
0
0
0
0
0
8
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
8
36
0
0
% I
% Lys:
8
0
0
8
0
15
36
8
22
8
8
8
8
0
0
% K
% Leu:
0
0
0
0
0
0
15
0
0
0
15
8
8
50
0
% L
% Met:
0
8
0
0
0
0
0
0
0
0
0
0
8
0
0
% M
% Asn:
29
0
0
0
0
8
8
0
0
0
0
8
0
0
8
% N
% Pro:
0
22
0
36
0
29
15
0
15
15
0
0
0
0
0
% P
% Gln:
8
8
0
0
0
0
8
0
0
0
0
0
0
8
0
% Q
% Arg:
0
0
0
8
0
8
0
0
8
0
0
0
0
8
0
% R
% Ser:
22
0
0
0
29
8
0
65
29
15
0
0
0
15
8
% S
% Thr:
0
0
0
0
0
8
8
8
8
43
8
8
0
0
0
% T
% Val:
8
0
22
0
0
0
0
0
0
0
8
0
15
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
58
% _