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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PDE6B
All Species:
33.94
Human Site:
T281
Identified Species:
57.44
UniProt:
P35913
Number Species:
13
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P35913
NP_000274.2
854
98336
T281
S
V
G
L
L
D
M
T
K
E
K
E
F
F
D
Chimpanzee
Pan troglodytes
XP_518030
860
99527
T283
S
V
G
L
L
D
M
T
K
Q
K
E
F
F
D
Rhesus Macaque
Macaca mulatta
XP_001094732
854
97937
T281
S
V
G
L
L
D
M
T
K
E
K
E
F
F
D
Dog
Lupus familis
XP_543934
846
97567
T270
S
I
G
L
L
D
M
T
K
E
K
E
F
Y
D
Cat
Felis silvestris
Mouse
Mus musculus
P23440
856
98483
T281
S
V
G
L
L
D
M
T
K
E
K
E
F
F
D
Rat
Rattus norvegicus
Q8VID6
935
104553
P346
A
Q
A
I
N
K
V
P
E
G
A
P
F
T
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512709
856
98818
S281
S
V
G
L
L
D
M
S
K
E
K
E
F
F
D
Chicken
Gallus gallus
P52731
862
99990
T285
S
V
G
L
L
D
M
T
K
E
K
E
F
Y
D
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_685002
854
98605
T282
S
V
G
L
L
D
M
T
K
E
K
E
F
F
D
Tiger Blowfish
Takifugu rubipres
Q1KKS3
903
102001
R339
A
S
R
K
E
Y
D
R
S
R
A
L
L
E
V
Fruit Fly
Dros. melanogaster
Q9VFI9
1131
125621
D473
S
V
F
L
V
D
L
D
C
C
E
A
S
H
L
Honey Bee
Apis mellifera
XP_394107
1016
115998
D412
A
V
Y
L
L
D
L
D
C
G
E
A
G
H
L
Nematode Worm
Caenorhab. elegans
P91119
710
81117
I211
G
Q
D
I
H
E
N
I
A
K
Q
R
K
L
S
Sea Urchin
Strong. purpuratus
NP_001029121
949
108476
T362
M
V
F
I
L
E
T
T
E
E
S
Y
L
P
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
71.4
93.9
63.8
N.A.
92.5
24.9
N.A.
86.2
64.5
N.A.
76.1
24.2
23.7
25.6
23.8
32.9
Protein Similarity:
100
82.3
96.7
79.1
N.A.
96.2
44.1
N.A.
92.6
78.8
N.A.
85.1
43.7
41.2
44.6
42.3
53.2
P-Site Identity:
100
93.3
100
86.6
N.A.
100
6.6
N.A.
93.3
93.3
N.A.
100
0
26.6
26.6
0
26.6
P-Site Similarity:
100
100
100
100
N.A.
100
40
N.A.
100
100
N.A.
100
6.6
46.6
46.6
26.6
46.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
22
0
8
0
0
0
0
0
8
0
15
15
0
0
8
% A
% Cys:
0
0
0
0
0
0
0
0
15
8
0
0
0
0
0
% C
% Asp:
0
0
8
0
0
72
8
15
0
0
0
0
0
0
58
% D
% Glu:
0
0
0
0
8
15
0
0
15
58
15
58
0
8
8
% E
% Phe:
0
0
15
0
0
0
0
0
0
0
0
0
65
43
0
% F
% Gly:
8
0
58
0
0
0
0
0
0
15
0
0
8
0
0
% G
% His:
0
0
0
0
8
0
0
0
0
0
0
0
0
15
0
% H
% Ile:
0
8
0
22
0
0
0
8
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
8
0
8
0
0
58
8
58
0
8
0
0
% K
% Leu:
0
0
0
72
72
0
15
0
0
0
0
8
15
8
15
% L
% Met:
8
0
0
0
0
0
58
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
8
0
8
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
8
0
0
0
8
0
8
0
% P
% Gln:
0
15
0
0
0
0
0
0
0
8
8
0
0
0
0
% Q
% Arg:
0
0
8
0
0
0
0
8
0
8
0
8
0
0
0
% R
% Ser:
65
8
0
0
0
0
0
8
8
0
8
0
8
0
8
% S
% Thr:
0
0
0
0
0
0
8
58
0
0
0
0
0
8
0
% T
% Val:
0
72
0
0
8
0
8
0
0
0
0
0
0
0
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
8
0
0
8
0
0
0
0
0
8
0
15
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _