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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PDE6B
All Species:
28.18
Human Site:
Y319
Identified Species:
47.69
UniProt:
P35913
Number Species:
13
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P35913
NP_000274.2
854
98336
Y319
V
F
Y
K
V
I
D
Y
V
L
H
G
K
E
E
Chimpanzee
Pan troglodytes
XP_518030
860
99527
Y321
N
F
Y
K
V
I
D
Y
I
L
H
G
K
E
D
Rhesus Macaque
Macaca mulatta
XP_001094732
854
97937
I319
R
A
Q
L
V
R
G
I
V
V
G
R
R
E
K
Dog
Lupus familis
XP_543934
846
97567
Y308
I
F
Y
K
I
I
D
Y
I
L
H
G
K
E
E
Cat
Felis silvestris
Mouse
Mus musculus
P23440
856
98483
Y319
V
F
Y
K
V
I
D
Y
I
L
H
G
K
E
D
Rat
Rattus norvegicus
Q8VID6
935
104553
E384
A
A
S
R
K
E
Y
E
R
S
R
A
L
L
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512709
856
98818
Y319
L
F
Y
K
V
I
D
Y
I
L
H
G
K
E
D
Chicken
Gallus gallus
P52731
862
99990
Y323
N
F
Y
K
I
I
D
Y
I
L
H
G
K
E
E
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_685002
854
98605
Y320
I
F
Y
K
V
I
D
Y
I
L
H
G
K
E
D
Tiger Blowfish
Takifugu rubipres
Q1KKS3
903
102001
C377
T
L
L
K
C
E
R
C
S
V
Q
L
L
E
D
Fruit Fly
Dros. melanogaster
Q9VFI9
1131
125621
T511
K
K
M
R
N
R
F
T
V
L
F
E
L
G
G
Honey Bee
Apis mellifera
XP_394107
1016
115998
T450
T
N
D
G
N
K
F
T
T
I
F
E
M
D
N
Nematode Worm
Caenorhab. elegans
P91119
710
81117
L249
V
M
N
F
A
Q
K
L
V
D
A
D
R
A
S
Sea Urchin
Strong. purpuratus
NP_001029121
949
108476
L400
D
V
K
N
I
S
F
L
K
G
F
E
L
T
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
71.4
93.9
63.8
N.A.
92.5
24.9
N.A.
86.2
64.5
N.A.
76.1
24.2
23.7
25.6
23.8
32.9
Protein Similarity:
100
82.3
96.7
79.1
N.A.
96.2
44.1
N.A.
92.6
78.8
N.A.
85.1
43.7
41.2
44.6
42.3
53.2
P-Site Identity:
100
80
20
80
N.A.
86.6
6.6
N.A.
80
80
N.A.
80
13.3
13.3
0
13.3
0
P-Site Similarity:
100
93.3
40
100
N.A.
100
13.3
N.A.
100
93.3
N.A.
100
26.6
20
13.3
20
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
15
0
0
8
0
0
0
0
0
8
8
0
8
0
% A
% Cys:
0
0
0
0
8
0
0
8
0
0
0
0
0
0
0
% C
% Asp:
8
0
8
0
0
0
50
0
0
8
0
8
0
8
43
% D
% Glu:
0
0
0
0
0
15
0
8
0
0
0
22
0
65
29
% E
% Phe:
0
50
0
8
0
0
22
0
0
0
22
0
0
0
0
% F
% Gly:
0
0
0
8
0
0
8
0
0
8
8
50
0
8
8
% G
% His:
0
0
0
0
0
0
0
0
0
0
50
0
0
0
0
% H
% Ile:
15
0
0
0
22
50
0
8
43
8
0
0
0
0
0
% I
% Lys:
8
8
8
58
8
8
8
0
8
0
0
0
50
0
8
% K
% Leu:
8
8
8
8
0
0
0
15
0
58
0
8
29
8
0
% L
% Met:
0
8
8
0
0
0
0
0
0
0
0
0
8
0
0
% M
% Asn:
15
8
8
8
15
0
0
0
0
0
0
0
0
0
8
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
8
0
0
8
0
0
0
0
8
0
0
0
0
% Q
% Arg:
8
0
0
15
0
15
8
0
8
0
8
8
15
0
0
% R
% Ser:
0
0
8
0
0
8
0
0
8
8
0
0
0
0
8
% S
% Thr:
15
0
0
0
0
0
0
15
8
0
0
0
0
8
0
% T
% Val:
22
8
0
0
43
0
0
0
29
15
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
50
0
0
0
8
50
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _