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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PDE6B All Species: 23.64
Human Site: Y97 Identified Species: 40
UniProt: P35913 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P35913 NP_000274.2 854 98336 Y97 D R C S L F M Y R Q R N G V A
Chimpanzee Pan troglodytes XP_518030 860 99527 Y99 D R M S L F M Y R T R N G I A
Rhesus Macaque Macaca mulatta XP_001094732 854 97937 Y97 D R C S L F M Y R Q R N G V A
Dog Lupus familis XP_543934 846 97567 A96 R N G T P E V A S R L L D I T
Cat Felis silvestris
Mouse Mus musculus P23440 856 98483 Y97 D R C S L F M Y R Q R N G I A
Rat Rattus norvegicus Q8VID6 935 104553 A169 S S L P P T T A H I L S A L L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001512709 856 98818 Y97 E R C S L F M Y R Q R N G V A
Chicken Gallus gallus P52731 862 99990 C101 D R C S M F I C R S R N G I P
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_685002 854 98605 Y98 D R C S L F M Y R Q R N G I A
Tiger Blowfish Takifugu rubipres Q1KKS3 903 102001 A127 S S L P P T T A H I L S A L L
Fruit Fly Dros. melanogaster Q9VFI9 1131 125621 A286 D R G S L F L A K G T P T N K
Honey Bee Apis mellifera XP_394107 1016 115998 A225 D R G S L F L A K G P L E D R
Nematode Worm Caenorhab. elegans P91119 710 81117 T39 K R W A V R R T M K Y K N V K
Sea Urchin Strong. purpuratus NP_001029121 949 108476 A157 D R C S L F L A R G T K D R R
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 71.4 93.9 63.8 N.A. 92.5 24.9 N.A. 86.2 64.5 N.A. 76.1 24.2 23.7 25.6 23.8 32.9
Protein Similarity: 100 82.3 96.7 79.1 N.A. 96.2 44.1 N.A. 92.6 78.8 N.A. 85.1 43.7 41.2 44.6 42.3 53.2
P-Site Identity: 100 80 100 0 N.A. 93.3 0 N.A. 93.3 60 N.A. 93.3 0 33.3 33.3 13.3 46.6
P-Site Similarity: 100 86.6 100 26.6 N.A. 100 13.3 N.A. 100 80 N.A. 100 13.3 46.6 46.6 33.3 53.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 8 0 0 0 43 0 0 0 0 15 0 43 % A
% Cys: 0 0 50 0 0 0 0 8 0 0 0 0 0 0 0 % C
% Asp: 65 0 0 0 0 0 0 0 0 0 0 0 15 8 0 % D
% Glu: 8 0 0 0 0 8 0 0 0 0 0 0 8 0 0 % E
% Phe: 0 0 0 0 0 72 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 22 0 0 0 0 0 0 22 0 0 50 0 0 % G
% His: 0 0 0 0 0 0 0 0 15 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 8 0 0 15 0 0 0 36 0 % I
% Lys: 8 0 0 0 0 0 0 0 15 8 0 15 0 0 15 % K
% Leu: 0 0 15 0 65 0 22 0 0 0 22 15 0 15 15 % L
% Met: 0 0 8 0 8 0 43 0 8 0 0 0 0 0 0 % M
% Asn: 0 8 0 0 0 0 0 0 0 0 0 50 8 8 0 % N
% Pro: 0 0 0 15 22 0 0 0 0 0 8 8 0 0 8 % P
% Gln: 0 0 0 0 0 0 0 0 0 36 0 0 0 0 0 % Q
% Arg: 8 79 0 0 0 8 8 0 58 8 50 0 0 8 15 % R
% Ser: 15 15 0 72 0 0 0 0 8 8 0 15 0 0 0 % S
% Thr: 0 0 0 8 0 15 15 8 0 8 15 0 8 0 8 % T
% Val: 0 0 0 0 8 0 8 0 0 0 0 0 0 29 0 % V
% Trp: 0 0 8 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 43 0 0 8 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _