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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: KDR All Species: 14.55
Human Site: S1260 Identified Species: 32
UniProt: P35968 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0.1
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P35968 NP_002244.1 1356 151527 S1260 P D D N Q T D S G M V L A S E
Chimpanzee Pan troglodytes XP_517284 1466 163299 S1370 P D D N Q T D S G M V L A S E
Rhesus Macaque Macaca mulatta XP_001086814 1466 163393 S1370 P D D N Q T D S G M V L A S E
Dog Lupus familis XP_538585 1362 152583 L1261 F E E F P M T L T T Y K A S V
Cat Felis silvestris
Mouse Mus musculus P35918 1367 152498 S1258 P D D S Q T D S G M V L A S E
Rat Rattus norvegicus O08775 1343 150375 V1247 L E E P E V K V I P D D S Q T
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506890 1760 194882 V1665 P L E P E I K V I P D D N Q T
Chicken Gallus gallus Q8QHL3 1327 149408 Q1232 K L V F N D Y Q A D S G M V L
Frog Xenopus laevis Q91909 954 106841 V859 S P Y P R I P V D S K F Y K M
Zebra Danio Brachydanio rerio Q5GIT4 1357 153023 D1262 T V M D G H V D C G V G L S R
Tiger Blowfish Takifugu rubipres Q8AXC6 984 110714 Y889 E F A P S E M Y Q I M R S C W
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 92.2 91.4 43.1 N.A. 84.7 85.6 N.A. 58.5 44.2 25.8 50.1 27.8 N.A. N.A. N.A. N.A.
Protein Similarity: 100 92.2 92 59.6 N.A. 90.2 91.6 N.A. 65.2 60.1 41.6 65.3 43.2 N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 100 13.3 N.A. 93.3 0 N.A. 6.6 0 0 13.3 0 N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 100 26.6 N.A. 100 26.6 N.A. 20 0 6.6 20 20 N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 10 0 0 0 0 0 10 0 0 0 46 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 10 0 0 0 0 10 0 % C
% Asp: 0 37 37 10 0 10 37 10 10 10 19 19 0 0 0 % D
% Glu: 10 19 28 0 19 10 0 0 0 0 0 0 0 0 37 % E
% Phe: 10 10 0 19 0 0 0 0 0 0 0 10 0 0 0 % F
% Gly: 0 0 0 0 10 0 0 0 37 10 0 19 0 0 0 % G
% His: 0 0 0 0 0 10 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 19 0 0 19 10 0 0 0 0 0 % I
% Lys: 10 0 0 0 0 0 19 0 0 0 10 10 0 10 0 % K
% Leu: 10 19 0 0 0 0 0 10 0 0 0 37 10 0 10 % L
% Met: 0 0 10 0 0 10 10 0 0 37 10 0 10 0 10 % M
% Asn: 0 0 0 28 10 0 0 0 0 0 0 0 10 0 0 % N
% Pro: 46 10 0 37 10 0 10 0 0 19 0 0 0 0 0 % P
% Gln: 0 0 0 0 37 0 0 10 10 0 0 0 0 19 0 % Q
% Arg: 0 0 0 0 10 0 0 0 0 0 0 10 0 0 10 % R
% Ser: 10 0 0 10 10 0 0 37 0 10 10 0 19 55 0 % S
% Thr: 10 0 0 0 0 37 10 0 10 10 0 0 0 0 19 % T
% Val: 0 10 10 0 0 10 10 28 0 0 46 0 0 10 10 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10 % W
% Tyr: 0 0 10 0 0 0 10 10 0 0 10 0 10 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _