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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PSMC2
All Species:
45.45
Human Site:
S175
Identified Species:
71.43
UniProt:
P35998
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P35998
NP_002794.1
433
48634
S175
E
K
P
D
V
T
Y
S
D
V
G
G
C
K
E
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_533103
906
98310
S648
E
K
P
D
V
T
Y
S
D
V
G
G
C
K
E
Cat
Felis silvestris
Mouse
Mus musculus
P46471
433
48629
S175
E
K
P
D
V
T
Y
S
D
V
G
G
C
K
E
Rat
Rattus norvegicus
Q63347
433
48556
S175
E
K
P
D
V
T
Y
S
D
V
G
G
C
K
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507929
476
53606
S218
E
K
P
D
V
T
Y
S
D
V
G
G
C
K
E
Chicken
Gallus gallus
NP_001006225
433
48643
S175
E
K
P
D
V
T
Y
S
D
V
G
G
C
K
E
Frog
Xenopus laevis
P46472
433
48645
S175
E
K
P
D
V
T
Y
S
D
V
G
G
C
K
E
Zebra Danio
Brachydanio rerio
NP_957260
433
48685
S175
E
K
P
D
V
T
Y
S
D
V
G
G
C
K
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
O18413
405
45839
K161
D
K
Q
I
K
E
I
K
E
V
I
E
L
P
V
Honey Bee
Apis mellifera
XP_623743
434
48438
S176
E
K
P
D
V
T
Y
S
D
V
G
G
C
K
E
Nematode Worm
Caenorhab. elegans
Q18787
435
48592
S177
E
K
P
D
V
T
Y
S
D
V
G
G
C
K
D
Sea Urchin
Strong. purpuratus
XP_001190601
414
46080
R169
K
E
Q
I
D
K
L
R
E
V
V
E
T
P
L
Poplar Tree
Populus trichocarpa
XP_002308501
429
47955
N171
E
K
P
D
V
T
Y
N
D
V
G
G
C
K
E
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9SSB5
426
47785
N168
E
K
P
D
V
T
Y
N
D
V
G
G
C
K
E
Baker's Yeast
Sacchar. cerevisiae
P33299
467
51964
S209
E
K
P
D
V
T
Y
S
D
V
G
G
C
K
D
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
N.A.
47.7
N.A.
99.7
99.7
N.A.
88.4
99.5
99
98.8
N.A.
44.3
91.9
85.5
86.3
Protein Similarity:
100
N.A.
N.A.
47.7
N.A.
100
99.7
N.A.
89.9
100
100
99.5
N.A.
62.5
97
93.5
91.9
P-Site Identity:
100
N.A.
N.A.
100
N.A.
100
100
N.A.
100
100
100
100
N.A.
13.3
100
93.3
6.6
P-Site Similarity:
100
N.A.
N.A.
100
N.A.
100
100
N.A.
100
100
100
100
N.A.
26.6
100
100
26.6
Percent
Protein Identity:
78.9
N.A.
N.A.
79.2
70
N.A.
Protein Similarity:
87.5
N.A.
N.A.
88.2
81.3
N.A.
P-Site Identity:
93.3
N.A.
N.A.
93.3
93.3
N.A.
P-Site Similarity:
100
N.A.
N.A.
100
100
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
87
0
0
% C
% Asp:
7
0
0
87
7
0
0
0
87
0
0
0
0
0
14
% D
% Glu:
87
7
0
0
0
7
0
0
14
0
0
14
0
0
74
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
87
87
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
14
0
0
7
0
0
0
7
0
0
0
0
% I
% Lys:
7
94
0
0
7
7
0
7
0
0
0
0
0
87
0
% K
% Leu:
0
0
0
0
0
0
7
0
0
0
0
0
7
0
7
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
14
0
0
0
0
0
0
0
% N
% Pro:
0
0
87
0
0
0
0
0
0
0
0
0
0
14
0
% P
% Gln:
0
0
14
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
7
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
74
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
87
0
0
0
0
0
0
7
0
0
% T
% Val:
0
0
0
0
87
0
0
0
0
100
7
0
0
0
7
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
87
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _