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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PSMC2 All Species: 36.36
Human Site: S344 Identified Species: 57.14
UniProt: P35998 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P35998 NP_002794.1 433 48634 S344 L D R K I E F S L P D L E G R
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_533103 906 98310 S817 L D R K I E F S L P D L E G R
Cat Felis silvestris
Mouse Mus musculus P46471 433 48629 S344 L D R K I E F S L P D L E G R
Rat Rattus norvegicus Q63347 433 48556 S344 L D R K I E F S L P D L E G R
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001507929 476 53606 S387 L D R K I E F S L P D L E G R
Chicken Gallus gallus NP_001006225 433 48643 S344 L D R K I E F S L P D L E G R
Frog Xenopus laevis P46472 433 48645 S344 L D R K I E F S L P D L E G R
Zebra Danio Brachydanio rerio NP_957260 433 48685 S344 L D R K I E F S L P D L E G R
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster O18413 405 45839 P317 I D R K I E F P P P N E E A R
Honey Bee Apis mellifera XP_623743 434 48438 G345 L D R K V E F G L P D L E G R
Nematode Worm Caenorhab. elegans Q18787 435 48592 A346 L D R K V E F A L P D L A G R
Sea Urchin Strong. purpuratus XP_001190601 414 46080 G325 L D R K V E F G L P D L E G R
Poplar Tree Populus trichocarpa XP_002308501 429 47955 G340 L D R K V E F G L P D L E S R
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9SSB5 426 47785 G337 L D R K V E F G L P D L E S R
Baker's Yeast Sacchar. cerevisiae P33299 467 51964 S378 I D R K V E F S L P D L E G R
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. N.A. 47.7 N.A. 99.7 99.7 N.A. 88.4 99.5 99 98.8 N.A. 44.3 91.9 85.5 86.3
Protein Similarity: 100 N.A. N.A. 47.7 N.A. 100 99.7 N.A. 89.9 100 100 99.5 N.A. 62.5 97 93.5 91.9
P-Site Identity: 100 N.A. N.A. 100 N.A. 100 100 N.A. 100 100 100 100 N.A. 60 86.6 80 86.6
P-Site Similarity: 100 N.A. N.A. 100 N.A. 100 100 N.A. 100 100 100 100 N.A. 73.3 93.3 93.3 93.3
Percent
Protein Identity: 78.9 N.A. N.A. 79.2 70 N.A.
Protein Similarity: 87.5 N.A. N.A. 88.2 81.3 N.A.
P-Site Identity: 80 N.A. N.A. 80 86.6 N.A.
P-Site Similarity: 86.6 N.A. N.A. 86.6 100 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 7 0 0 0 0 7 7 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 100 0 0 0 0 0 0 0 0 94 0 0 0 0 % D
% Glu: 0 0 0 0 0 100 0 0 0 0 0 7 94 0 0 % E
% Phe: 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 27 0 0 0 0 0 80 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 14 0 0 0 60 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 87 0 0 0 0 0 0 0 94 0 0 94 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 7 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 7 7 100 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 100 0 0 0 0 0 0 0 0 0 0 0 100 % R
% Ser: 0 0 0 0 0 0 0 60 0 0 0 0 0 14 0 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % T
% Val: 0 0 0 0 40 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _