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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PSMC2 All Species: 40.91
Human Site: T193 Identified Species: 64.29
UniProt: P35998 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P35998 NP_002794.1 433 48634 T193 K L R E V V E T P L L H P E R
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_533103 906 98310 T666 K L R E V V E T P L L H P E R
Cat Felis silvestris
Mouse Mus musculus P46471 433 48629 T193 K L R E V V E T P L L H P E R
Rat Rattus norvegicus Q63347 433 48556 T193 K L R E V V E T P L L H P E R
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001507929 476 53606 T236 K L R E V V E T P L L H P E R
Chicken Gallus gallus NP_001006225 433 48643 T193 K L R E V V E T P L L H P E R
Frog Xenopus laevis P46472 433 48645 T193 K L R E V V E T P L L H P E R
Zebra Danio Brachydanio rerio NP_957260 433 48685 T193 K L R E V V E T P L L H P E R
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster O18413 405 45839 A176 K H P E L F D A L G I A Q P K
Honey Bee Apis mellifera XP_623743 434 48438 T194 K L R E V V E T P L L H P E K
Nematode Worm Caenorhab. elegans Q18787 435 48592 T195 K L R E V V E T P L L H P E R
Sea Urchin Strong. purpuratus XP_001190601 414 46080 N184 L H P E R F V N L G I E P P K
Poplar Tree Populus trichocarpa XP_002308501 429 47955 L189 K M R E V V E L P M L H P E K
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9SSB5 426 47785 L186 K M R E V V E L P M L H P E K
Baker's Yeast Sacchar. cerevisiae P33299 467 51964 L227 K L R E V V E L P L L S P E R
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. N.A. 47.7 N.A. 99.7 99.7 N.A. 88.4 99.5 99 98.8 N.A. 44.3 91.9 85.5 86.3
Protein Similarity: 100 N.A. N.A. 47.7 N.A. 100 99.7 N.A. 89.9 100 100 99.5 N.A. 62.5 97 93.5 91.9
P-Site Identity: 100 N.A. N.A. 100 N.A. 100 100 N.A. 100 100 100 100 N.A. 13.3 93.3 100 13.3
P-Site Similarity: 100 N.A. N.A. 100 N.A. 100 100 N.A. 100 100 100 100 N.A. 40 100 100 26.6
Percent
Protein Identity: 78.9 N.A. N.A. 79.2 70 N.A.
Protein Similarity: 87.5 N.A. N.A. 88.2 81.3 N.A.
P-Site Identity: 73.3 N.A. N.A. 73.3 86.6 N.A.
P-Site Similarity: 93.3 N.A. N.A. 93.3 86.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 7 0 0 0 7 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 7 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 100 0 0 87 0 0 0 0 7 0 87 0 % E
% Phe: 0 0 0 0 0 14 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 14 0 0 0 0 0 % G
% His: 0 14 0 0 0 0 0 0 0 0 0 80 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 14 0 0 0 0 % I
% Lys: 94 0 0 0 0 0 0 0 0 0 0 0 0 0 34 % K
% Leu: 7 74 0 0 7 0 0 20 14 74 87 0 0 0 0 % L
% Met: 0 14 0 0 0 0 0 0 0 14 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 7 0 0 0 0 0 0 0 % N
% Pro: 0 0 14 0 0 0 0 0 87 0 0 0 94 14 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 7 0 0 % Q
% Arg: 0 0 87 0 7 0 0 0 0 0 0 0 0 0 67 % R
% Ser: 0 0 0 0 0 0 0 0 0 0 0 7 0 0 0 % S
% Thr: 0 0 0 0 0 0 0 67 0 0 0 0 0 0 0 % T
% Val: 0 0 0 0 87 87 7 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _