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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PSMC2 All Species: 47.27
Human Site: Y41 Identified Species: 74.29
UniProt: P35998 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P35998 NP_002794.1 433 48634 Y41 K T Y G Q S T Y S R Q I K Q V
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_533103 906 98310 Y514 K T Y G Q S T Y S R Q I K Q V
Cat Felis silvestris
Mouse Mus musculus P46471 433 48629 Y41 K T Y G Q S T Y S R Q I K Q V
Rat Rattus norvegicus Q63347 433 48556 Y41 K T Y G Q S T Y S R Q I K Q V
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001507929 476 53606 Y84 K T Y G Q S T Y S R Q I K Q V
Chicken Gallus gallus NP_001006225 433 48643 Y41 K T Y G Q S T Y S R Q I K Q V
Frog Xenopus laevis P46472 433 48645 Y41 K T Y G Q S T Y S R Q I K Q V
Zebra Danio Brachydanio rerio NP_957260 433 48685 Y41 K T Y G Q S T Y S R Q I K Q V
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster O18413 405 45839 V34 I E E L Q L V V A E K H Q N L
Honey Bee Apis mellifera XP_623743 434 48438 Y42 K T Y G Q G Q Y T K S I K A V
Nematode Worm Caenorhab. elegans Q18787 435 48592 Y43 K R Y G Q G P Y A E Q L K T L
Sea Urchin Strong. purpuratus XP_001190601 414 46080 V37 E D D I Q A I V K R V N E L T
Poplar Tree Populus trichocarpa XP_002308501 429 47955 Y37 K T Y G L G P Y S N S I K K E
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9SSB5 426 47785 Y34 K T Y G L G P Y S A P I K K V
Baker's Yeast Sacchar. cerevisiae P33299 467 51964 Y45 K S Y G A A P Y A A K L K Q T
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. N.A. 47.7 N.A. 99.7 99.7 N.A. 88.4 99.5 99 98.8 N.A. 44.3 91.9 85.5 86.3
Protein Similarity: 100 N.A. N.A. 47.7 N.A. 100 99.7 N.A. 89.9 100 100 99.5 N.A. 62.5 97 93.5 91.9
P-Site Identity: 100 N.A. N.A. 100 N.A. 100 100 N.A. 100 100 100 100 N.A. 6.6 60 46.6 13.3
P-Site Similarity: 100 N.A. N.A. 100 N.A. 100 100 N.A. 100 100 100 100 N.A. 33.3 73.3 66.6 33.3
Percent
Protein Identity: 78.9 N.A. N.A. 79.2 70 N.A.
Protein Similarity: 87.5 N.A. N.A. 88.2 81.3 N.A.
P-Site Identity: 53.3 N.A. N.A. 60 40 N.A.
P-Site Similarity: 60 N.A. N.A. 66.6 73.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 7 14 0 0 20 14 0 0 0 7 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 7 7 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 7 7 7 0 0 0 0 0 0 14 0 0 7 0 7 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 87 0 27 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 7 0 0 0 % H
% Ile: 7 0 0 7 0 0 7 0 0 0 0 74 0 0 0 % I
% Lys: 87 0 0 0 0 0 0 0 7 7 14 0 87 14 0 % K
% Leu: 0 0 0 7 14 7 0 0 0 0 0 14 0 7 14 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 7 0 7 0 7 0 % N
% Pro: 0 0 0 0 0 0 27 0 0 0 7 0 0 0 0 % P
% Gln: 0 0 0 0 80 0 7 0 0 0 60 0 7 60 0 % Q
% Arg: 0 7 0 0 0 0 0 0 0 60 0 0 0 0 0 % R
% Ser: 0 7 0 0 0 54 0 0 67 0 14 0 0 0 0 % S
% Thr: 0 74 0 0 0 0 54 0 7 0 0 0 0 7 14 % T
% Val: 0 0 0 0 0 0 7 14 0 0 7 0 0 0 67 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 87 0 0 0 0 87 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _