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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SLC16A2 All Species: 17.27
Human Site: S380 Identified Species: 38
UniProt: P36021 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0.1
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P36021 NP_006508.1 539 59511 S380 V S G H I S D S I P G L K K I
Chimpanzee Pan troglodytes XP_518692 514 55679 Y351 L F G R I A D Y V P G V K K V
Rhesus Macaque Macaca mulatta XP_001096017 611 66332 S452 V S G H I S D S I P G L K K I
Dog Lupus familis XP_549084 411 45045 F298 F L G L C D G F F I T I M A P
Cat Felis silvestris
Mouse Mus musculus O70324 545 60007 S386 V S G H I S D S I P G L K K I
Rat Rattus norvegicus Q8K1P8 545 60100 S386 V S G H I S D S I P G L K K I
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001505298 446 49280 D332 C L F M G L F D G C F I S I M
Chicken Gallus gallus XP_426274 509 55120 C350 I S G R T G D C I P G L K K I
Frog Xenopus laevis Q6GM59 460 50319 Q337 L P I L T C F Q L L V P F S V
Zebra Danio Brachydanio rerio A1L1W9 505 54987 V351 Y V P G V N K V F L Q V S S F
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_397345 611 66736 N387 I A D L P R V N R I L L Q Q I
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 51.9 87.5 71.6 N.A. 93.7 92.6 N.A. 43.9 60.4 20 52.5 N.A. N.A. 29.7 N.A. N.A.
Protein Similarity: 100 65.8 87.7 73.8 N.A. 95.2 94.6 N.A. 55.8 71.2 36.1 66.9 N.A. N.A. 50 N.A. N.A.
P-Site Identity: 100 46.6 100 6.6 N.A. 100 100 N.A. 0 66.6 0 0 N.A. N.A. 13.3 N.A. N.A.
P-Site Similarity: 100 80 100 13.3 N.A. 100 100 N.A. 13.3 73.3 20 20 N.A. N.A. 46.6 N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 10 0 0 0 10 0 0 0 0 0 0 0 10 0 % A
% Cys: 10 0 0 0 10 10 0 10 0 10 0 0 0 0 0 % C
% Asp: 0 0 10 0 0 10 55 10 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 10 10 10 0 0 0 19 10 19 0 10 0 10 0 10 % F
% Gly: 0 0 64 10 10 10 10 0 10 0 55 0 0 0 0 % G
% His: 0 0 0 37 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 19 0 10 0 46 0 0 0 46 19 0 19 0 10 55 % I
% Lys: 0 0 0 0 0 0 10 0 0 0 0 0 55 55 0 % K
% Leu: 19 19 0 28 0 10 0 0 10 19 10 55 0 0 0 % L
% Met: 0 0 0 10 0 0 0 0 0 0 0 0 10 0 10 % M
% Asn: 0 0 0 0 0 10 0 10 0 0 0 0 0 0 0 % N
% Pro: 0 10 10 0 10 0 0 0 0 55 0 10 0 0 10 % P
% Gln: 0 0 0 0 0 0 0 10 0 0 10 0 10 10 0 % Q
% Arg: 0 0 0 19 0 10 0 0 10 0 0 0 0 0 0 % R
% Ser: 0 46 0 0 0 37 0 37 0 0 0 0 19 19 0 % S
% Thr: 0 0 0 0 19 0 0 0 0 0 10 0 0 0 0 % T
% Val: 37 10 0 0 10 0 10 10 10 0 10 19 0 0 19 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 10 0 0 0 0 0 0 10 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _