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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: GJC1 All Species: 17.27
Human Site: S378 Identified Species: 42.22
UniProt: P36383 Number Species: 9
    Phosphosite Substitution
    Charge Score: -0.11
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P36383 NP_001073852.1 396 45470 S378 K V G S K A G S N K S T A S S
Chimpanzee Pan troglodytes XP_001147132 366 41479 S348 K V G S K A G S N K S T A S S
Rhesus Macaque Macaca mulatta XP_001114721 396 45465 S378 K V G S K A G S N K S T A S S
Dog Lupus familis XP_849012 349 38952 L332 R T P S G V R L P D T G Q R E
Cat Felis silvestris
Mouse Mus musculus P28229 396 45648 S378 K V G S K S G S N K S S I S S
Rat Rattus norvegicus Q80XF7 440 46972 V422 Q L A T K P R V G S E K G S T
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001509233 403 45390 C385 R T G S K G S C A R S S V S S
Chicken Gallus gallus P18861 394 45353 S376 E K K S K A G S N K S S A S S
Frog Xenopus laevis Q7ZXS7 377 43145 R360 S I A A E Q N R L N L A Q E K
Zebra Danio Brachydanio rerio Q92052 380 43560 N361 N G T A V E Q N R L N F A Q E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 89.3 99.7 44.9 N.A. 97.2 45.2 N.A. 74.6 83.5 54 51.2 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 90.4 100 60 N.A. 98.9 59.3 N.A. 83.6 92.1 69.1 66.1 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 100 6.6 N.A. 80 13.3 N.A. 40 73.3 0 6.6 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 100 20 N.A. 93.3 40 N.A. 60 86.6 20 26.6 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 20 20 0 40 0 0 10 0 0 10 50 0 0 % A
% Cys: 0 0 0 0 0 0 0 10 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 10 0 0 0 0 0 % D
% Glu: 10 0 0 0 10 10 0 0 0 0 10 0 0 10 20 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 10 0 0 0 % F
% Gly: 0 10 50 0 10 10 50 0 10 0 0 10 10 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 10 0 0 0 0 0 0 0 0 0 0 10 0 0 % I
% Lys: 40 10 10 0 70 0 0 0 0 50 0 10 0 0 10 % K
% Leu: 0 10 0 0 0 0 0 10 10 10 10 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 10 0 0 0 0 0 10 10 50 10 10 0 0 0 0 % N
% Pro: 0 0 10 0 0 10 0 0 10 0 0 0 0 0 0 % P
% Gln: 10 0 0 0 0 10 10 0 0 0 0 0 20 10 0 % Q
% Arg: 20 0 0 0 0 0 20 10 10 10 0 0 0 10 0 % R
% Ser: 10 0 0 70 0 10 10 50 0 10 60 30 0 70 60 % S
% Thr: 0 20 10 10 0 0 0 0 0 0 10 30 0 0 10 % T
% Val: 0 40 0 0 10 10 0 10 0 0 0 0 10 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _