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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TCF7
All Species:
4.55
Human Site:
T172
Identified Species:
14.29
UniProt:
P36402
Number Species:
7
Phosphosite Substitution
Charge Score:
0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P36402
NP_001128323.1
384
41642
T172
H
F
N
S
P
H
P
T
P
A
P
A
D
I
S
Chimpanzee
Pan troglodytes
XP_001152204
468
51079
T256
H
F
N
S
P
H
P
T
P
A
P
A
D
I
S
Rhesus Macaque
Macaca mulatta
XP_001107710
243
27468
P35
S
P
H
P
T
P
A
P
A
D
V
S
Q
K
Q
Dog
Lupus familis
XP_861809
272
30367
D64
H
P
T
S
A
P
A
D
I
S
Q
K
Q
G
V
Cat
Felis silvestris
Mouse
Mus musculus
Q00417
419
45447
P176
F
S
S
P
H
P
T
P
A
P
A
D
I
S
Q
Rat
Rattus norvegicus
Q9QXN1
397
44005
H171
S
P
G
S
H
P
S
H
I
P
S
E
V
N
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
P70062
554
60282
H188
S
P
G
T
P
P
G
H
L
S
P
E
I
D
P
Zebra Danio
Brachydanio rerio
Q800Q5
551
60400
L191
P
G
T
P
P
A
H
L
S
P
E
I
L
D
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
65.8
55.9
60.9
N.A.
79
46.5
N.A.
N.A.
N.A.
37.5
35.7
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
69.2
58
63
N.A.
80.9
57.1
N.A.
N.A.
N.A.
44.5
44.2
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
0
13.3
N.A.
0
6.6
N.A.
N.A.
N.A.
13.3
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
13.3
20
N.A.
6.6
6.6
N.A.
N.A.
N.A.
26.6
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
13
13
25
0
25
25
13
25
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
13
0
13
0
13
25
25
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
13
25
0
0
0
% E
% Phe:
13
25
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
13
25
0
0
0
13
0
0
0
0
0
0
13
0
% G
% His:
38
0
13
0
25
25
13
25
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
25
0
0
13
25
25
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
13
0
13
0
% K
% Leu:
0
0
0
0
0
0
0
13
13
0
0
0
13
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
25
0
0
0
0
0
0
0
0
0
0
13
0
% N
% Pro:
13
50
0
38
50
63
25
25
25
38
38
0
0
0
38
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
13
0
25
0
25
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
38
13
13
50
0
0
13
0
13
25
13
13
0
13
25
% S
% Thr:
0
0
25
13
13
0
13
25
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
13
0
13
0
13
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _