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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TCF7
All Species:
22.73
Human Site:
Y319
Identified Species:
71.43
UniProt:
P36402
Number Species:
7
Phosphosite Substitution
Charge Score:
0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P36402
NP_001128323.1
384
41642
Y319
R
E
E
Q
A
K
Y
Y
E
L
A
R
K
E
R
Chimpanzee
Pan troglodytes
XP_001152204
468
51079
Y403
R
E
E
Q
A
K
Y
Y
E
L
A
R
K
E
R
Rhesus Macaque
Macaca mulatta
XP_001107710
243
27468
Y179
R
E
E
Q
A
K
Y
Y
E
L
A
R
K
E
R
Dog
Lupus familis
XP_861809
272
30367
E208
E
E
Q
A
K
Y
Y
E
L
A
R
K
E
R
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q00417
419
45447
Y354
R
E
E
Q
A
K
Y
Y
E
L
A
R
K
E
R
Rat
Rattus norvegicus
Q9QXN1
397
44005
I327
T
L
K
E
S
A
A
I
N
Q
I
L
G
R
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
P70062
554
60282
Y374
R
E
E
Q
A
K
Y
Y
E
L
A
R
K
E
R
Zebra Danio
Brachydanio rerio
Q800Q5
551
60400
Y376
R
E
E
Q
A
K
Y
Y
E
L
A
R
K
E
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
65.8
55.9
60.9
N.A.
79
46.5
N.A.
N.A.
N.A.
37.5
35.7
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
69.2
58
63
N.A.
80.9
57.1
N.A.
N.A.
N.A.
44.5
44.2
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
13.3
N.A.
100
6.6
N.A.
N.A.
N.A.
100
100
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
40
N.A.
100
26.6
N.A.
N.A.
N.A.
100
100
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
13
75
13
13
0
0
13
75
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
13
88
75
13
0
0
0
13
75
0
0
0
13
75
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
13
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
13
0
0
13
0
0
0
0
% I
% Lys:
0
0
13
0
13
75
0
0
0
0
0
13
75
0
0
% K
% Leu:
0
13
0
0
0
0
0
0
13
75
0
13
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
13
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
13
75
0
0
0
0
0
13
0
0
0
0
13
% Q
% Arg:
75
0
0
0
0
0
0
0
0
0
13
75
0
25
88
% R
% Ser:
0
0
0
0
13
0
0
0
0
0
0
0
0
0
0
% S
% Thr:
13
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
13
88
75
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _