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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TRIM23 All Species: 22.73
Human Site: S492 Identified Species: 31.25
UniProt: P36406 Number Species: 16
    Phosphosite Substitution
    Charge Score: 0.19
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P36406 NP_001647.1 574 64067 S492 D R I S E A H S E L A K L L T
Chimpanzee Pan troglodytes XP_001163268 569 63670 S492 D R I S E A H S E L A K L L T
Rhesus Macaque Macaca mulatta XP_001085950 555 62151 R486 V D S S H R D R I S E A H S E
Dog Lupus familis XP_544360 574 63898 S492 D R V S E A H S E L A K L L T
Cat Felis silvestris
Mouse Mus musculus Q8BGX0 574 63913 S492 D R I S E A H S E L A K L L T
Rat Rattus norvegicus P36407 554 62169 S472 D R I S E A H S E L A K L L T
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001513714 492 55136 D423 L T E K E L R D A L L L I F A
Chicken Gallus gallus XP_424752 578 64116 S496 D R V S E A H S E L A K L L T
Frog Xenopus laevis P51643 181 20696 A112 E E L M R M L A E D E L R D A
Zebra Danio Brachydanio rerio NP_001070112 423 47701 D354 L T E K E L R D A L L L I F A
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P61209 182 20669 E113 E L M R M L A E D E L R D A V
Honey Bee Apis mellifera XP_392690 558 63627 N471 S R F K E A Q N E L S K I V N
Nematode Worm Caenorhab. elegans Q09654 539 60664 K460 E R F S E A I K E L N R V M S
Sea Urchin Strong. purpuratus XP_796010 578 64923 D496 D R L D E A Y D E L A I L M S
Poplar Tree Populus trichocarpa
Maize Zea mays P49076 181 20642 N112 D E L H R M L N E D E L R D A
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9SRC3 181 20574 N112 D E L H R M L N E D E L R D A
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa Q7RVM2 185 20961 E116 E L Q R M L N E D E L R D A L
Conservation
Percent
Protein Identity: 100 95.9 95.9 97.3 N.A. 97.7 94.2 N.A. 82.2 93.5 21.4 66 N.A. 21.9 46.8 35.1 61.4
Protein Similarity: 100 97 96.6 98.7 N.A. 98.6 95.4 N.A. 84.6 96.5 26.1 70 N.A. 26.1 65.8 53.3 77.1
P-Site Identity: 100 100 6.6 93.3 N.A. 100 100 N.A. 13.3 93.3 6.6 13.3 N.A. 0 40 40 53.3
P-Site Similarity: 100 100 6.6 100 N.A. 100 100 N.A. 20 100 26.6 20 N.A. 26.6 66.6 73.3 80
Percent
Protein Identity: N.A. 21.6 N.A. 22.1 N.A. 22.1
Protein Similarity: N.A. 26.1 N.A. 25.9 N.A. 26.4
P-Site Identity: N.A. 13.3 N.A. 13.3 N.A. 0
P-Site Similarity: N.A. 26.6 N.A. 26.6 N.A. 26.6
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 53 6 6 12 0 42 6 0 12 30 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 53 6 0 6 0 0 6 18 12 18 0 0 12 18 0 % D
% Glu: 24 18 12 0 65 0 0 12 71 12 24 0 0 0 6 % E
% Phe: 0 0 12 0 0 0 0 0 0 0 0 0 0 12 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 12 6 0 36 0 0 0 0 0 6 0 0 % H
% Ile: 0 0 24 0 0 0 6 0 6 0 0 6 18 0 0 % I
% Lys: 0 0 0 18 0 0 0 6 0 0 0 42 0 0 0 % K
% Leu: 12 12 24 0 0 24 18 0 0 65 24 30 42 36 6 % L
% Met: 0 0 6 6 12 18 0 0 0 0 0 0 0 12 0 % M
% Asn: 0 0 0 0 0 0 6 18 0 0 6 0 0 0 6 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 6 0 0 0 6 0 0 0 0 0 0 0 0 % Q
% Arg: 0 53 0 12 18 6 12 6 0 0 0 18 18 0 0 % R
% Ser: 6 0 6 48 0 0 0 36 0 6 6 0 0 6 12 % S
% Thr: 0 12 0 0 0 0 0 0 0 0 0 0 0 0 36 % T
% Val: 6 0 12 0 0 0 0 0 0 0 0 0 6 6 6 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 6 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _