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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MAP2K2
All Species:
20
Human Site:
S23
Identified Species:
36.67
UniProt:
P36507
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P36507
NP_109587.1
400
44424
S23
P
T
I
A
E
G
P
S
P
T
S
E
G
A
S
Chimpanzee
Pan troglodytes
Q9XT09
393
43428
A26
A
V
N
G
T
S
S
A
E
T
N
L
E
A
L
Rhesus Macaque
Macaca mulatta
XP_001118016
505
55560
S132
P
T
I
A
E
G
P
S
P
T
S
E
G
A
S
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
Q63932
401
44418
S23
P
T
I
A
E
G
P
S
P
T
S
E
G
A
S
Rat
Rattus norvegicus
P36506
400
44263
S23
P
T
I
A
E
G
P
S
P
T
S
E
G
A
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511248
391
43070
T25
V
T
H
R
C
D
P
T
G
G
I
R
V
Q
P
Chicken
Gallus gallus
Q90891
398
44059
G23
P
S
P
A
E
G
P
G
P
G
G
S
A
E
A
Frog
Xenopus laevis
Q05116
395
43724
T23
E
G
T
A
V
N
G
T
P
T
A
E
T
N
L
Zebra Danio
Brachydanio rerio
Q9DGE0
361
40575
N19
F
C
D
S
P
S
P
N
P
K
G
E
M
S
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q24324
396
43851
T27
A
A
A
T
V
A
P
T
P
P
F
K
T
P
S
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q10664
387
42776
E23
P
T
V
N
E
Q
S
E
S
G
E
A
T
A
E
Sea Urchin
Strong. purpuratus
XP_781505
412
45737
T34
G
Q
K
A
Q
S
A
T
T
A
T
E
K
S
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9S7U9
363
39830
F25
G
E
Q
S
I
T
K
F
L
T
Q
S
G
T
F
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
79.5
70.8
N.A.
N.A.
93.7
94
N.A.
64.5
93.5
79
32
N.A.
62.2
N.A.
51.7
63.5
Protein Similarity:
100
87.5
72.4
N.A.
N.A.
97.2
98
N.A.
73
96.2
87.5
50.7
N.A.
78.2
N.A.
66.5
75.7
P-Site Identity:
100
13.3
100
N.A.
N.A.
100
100
N.A.
13.3
40
26.6
20
N.A.
20
N.A.
26.6
13.3
P-Site Similarity:
100
26.6
100
N.A.
N.A.
100
100
N.A.
20
53.3
40
40
N.A.
33.3
N.A.
33.3
46.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
32.7
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
50.2
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
16
8
8
54
0
8
8
8
0
8
8
8
8
47
8
% A
% Cys:
0
8
0
0
8
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
8
0
0
8
0
0
0
0
0
0
0
0
0
% D
% Glu:
8
8
0
0
47
0
0
8
8
0
8
54
8
8
8
% E
% Phe:
8
0
0
0
0
0
0
8
0
0
8
0
0
0
8
% F
% Gly:
16
8
0
8
0
39
8
8
8
24
16
0
39
0
0
% G
% His:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
31
0
8
0
0
0
0
0
8
0
0
0
0
% I
% Lys:
0
0
8
0
0
0
8
0
0
8
0
8
8
0
0
% K
% Leu:
0
0
0
0
0
0
0
0
8
0
0
8
0
0
16
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% M
% Asn:
0
0
8
8
0
8
0
8
0
0
8
0
0
8
0
% N
% Pro:
47
0
8
0
8
0
62
0
62
8
0
0
0
8
8
% P
% Gln:
0
8
8
0
8
8
0
0
0
0
8
0
0
8
0
% Q
% Arg:
0
0
0
8
0
0
0
0
0
0
0
8
0
0
0
% R
% Ser:
0
8
0
16
0
24
16
31
8
0
31
16
0
16
39
% S
% Thr:
0
47
8
8
8
8
0
31
8
54
8
0
24
8
8
% T
% Val:
8
8
8
0
16
0
0
0
0
0
0
0
8
0
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _