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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MAP2K2
All Species:
9.7
Human Site:
T364
Identified Species:
17.78
UniProt:
P36507
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P36507
NP_109587.1
400
44424
T364
R
A
D
L
K
M
L
T
N
H
T
F
I
K
R
Chimpanzee
Pan troglodytes
Q9XT09
393
43428
M356
R
A
D
L
K
Q
L
M
V
H
A
F
I
K
R
Rhesus Macaque
Macaca mulatta
XP_001118016
505
55560
T469
R
A
D
L
K
M
L
T
N
H
T
F
I
K
R
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
Q63932
401
44418
M365
R
A
D
L
K
L
L
M
N
H
A
F
I
K
R
Rat
Rattus norvegicus
P36506
400
44263
T364
R
A
D
L
K
L
L
T
N
H
A
F
I
K
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511248
391
43070
M354
R
A
D
L
K
Q
L
M
V
H
A
F
I
K
R
Chicken
Gallus gallus
Q90891
398
44059
M362
R
A
D
L
K
M
L
M
N
H
T
F
I
K
R
Frog
Xenopus laevis
Q05116
395
43724
M358
R
A
D
L
K
Q
L
M
V
H
S
F
I
K
Q
Zebra Danio
Brachydanio rerio
Q9DGE0
361
40575
S326
S
Q
C
L
R
K
N
S
T
E
R
P
T
Y
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q24324
396
43851
L359
R
A
D
L
K
T
L
L
S
H
P
W
I
R
K
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q10664
387
42776
P345
S
K
C
L
R
K
L
P
S
E
R
A
T
L
K
Sea Urchin
Strong. purpuratus
XP_781505
412
45737
K372
R
A
D
L
K
K
L
K
V
H
T
F
A
I
M
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9S7U9
363
39830
M325
R
S
S
A
K
E
L
M
E
H
P
F
L
N
K
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
79.5
70.8
N.A.
N.A.
93.7
94
N.A.
64.5
93.5
79
32
N.A.
62.2
N.A.
51.7
63.5
Protein Similarity:
100
87.5
72.4
N.A.
N.A.
97.2
98
N.A.
73
96.2
87.5
50.7
N.A.
78.2
N.A.
66.5
75.7
P-Site Identity:
100
73.3
100
N.A.
N.A.
80
86.6
N.A.
73.3
93.3
66.6
6.6
N.A.
53.3
N.A.
13.3
60
P-Site Similarity:
100
73.3
100
N.A.
N.A.
86.6
93.3
N.A.
73.3
93.3
80
20
N.A.
80
N.A.
33.3
60
Percent
Protein Identity:
N.A.
N.A.
N.A.
32.7
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
50.2
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
33.3
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
53.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
77
0
8
0
0
0
0
0
0
31
8
8
0
0
% A
% Cys:
0
0
16
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
77
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
8
0
0
8
16
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
77
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
85
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
70
8
0
% I
% Lys:
0
8
0
0
85
24
0
8
0
0
0
0
0
62
24
% K
% Leu:
0
0
0
93
0
16
93
8
0
0
0
0
8
8
0
% L
% Met:
0
0
0
0
0
24
0
47
0
0
0
0
0
0
8
% M
% Asn:
0
0
0
0
0
0
8
0
39
0
0
0
0
8
0
% N
% Pro:
0
0
0
0
0
0
0
8
0
0
16
8
0
0
0
% P
% Gln:
0
8
0
0
0
24
0
0
0
0
0
0
0
0
8
% Q
% Arg:
85
0
0
0
16
0
0
0
0
0
16
0
0
8
54
% R
% Ser:
16
8
8
0
0
0
0
8
16
0
8
0
0
0
0
% S
% Thr:
0
0
0
0
0
8
0
24
8
0
31
0
16
0
8
% T
% Val:
0
0
0
0
0
0
0
0
31
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _