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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ATP5C1
All Species:
22.12
Human Site:
S214
Identified Species:
37.44
UniProt:
P36542
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.15
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P36542
NP_005165.1
298
32996
S214
N
T
V
A
S
A
D
S
M
S
I
Y
D
D
I
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001108136
297
32947
S214
N
T
I
A
S
A
E
S
M
S
I
Y
D
D
I
Dog
Lupus familis
XP_535193
298
33035
S214
E
T
V
A
S
A
E
S
M
S
I
Y
D
D
I
Cat
Felis silvestris
Mouse
Mus musculus
Q91VR2
298
32867
T214
N
T
I
A
T
A
E
T
M
S
I
Y
D
D
I
Rat
Rattus norvegicus
P35435
273
30172
M190
T
V
V
A
A
E
N
M
S
I
Y
D
D
I
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_417296
294
32705
S210
E
T
V
A
G
S
E
S
L
S
I
Y
D
D
I
Frog
Xenopus laevis
NP_001084748
294
32498
S211
D
T
V
A
S
S
E
S
I
S
V
Y
D
D
I
Zebra Danio
Brachydanio rerio
NP_956335
292
32116
N209
D
T
V
A
S
S
E
N
M
G
I
Y
D
D
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
O01666
297
32853
K213
S
T
V
E
K
S
E
K
L
A
V
Y
D
S
L
Honey Bee
Apis mellifera
XP_625078
296
32808
K212
N
A
V
V
S
A
P
K
L
S
L
Y
D
S
L
Nematode Worm
Caenorhab. elegans
NP_500214
299
32364
A216
E
A
I
K
A
K
E
A
L
S
T
Y
D
S
V
Sea Urchin
Strong. purpuratus
XP_784312
273
30282
M190
T
L
S
T
A
E
K
M
S
V
Y
D
D
I
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q96250
325
35429
Y238
K
L
G
E
L
D
S
Y
E
I
E
G
G
E
T
Baker's Yeast
Sacchar. cerevisiae
P38077
311
34332
F227
T
I
E
Q
S
P
S
F
G
K
F
E
I
D
T
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
97.9
95.6
N.A.
91.2
83.5
N.A.
N.A.
81.8
80.1
77.8
N.A.
55.7
54
55.5
52.6
Protein Similarity:
100
N.A.
99.3
98.6
N.A.
97.6
89.9
N.A.
N.A.
91.6
90.9
88.9
N.A.
74.1
74.5
73.5
71.8
P-Site Identity:
100
N.A.
86.6
86.6
N.A.
73.3
20
N.A.
N.A.
66.6
66.6
66.6
N.A.
26.6
46.6
20
6.6
P-Site Similarity:
100
N.A.
100
93.3
N.A.
100
33.3
N.A.
N.A.
86.6
100
93.3
N.A.
73.3
66.6
60
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
35
37.9
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
56
60.4
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
6.6
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
15
0
58
22
36
0
8
0
8
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
15
0
0
0
0
8
8
0
0
0
0
15
86
58
15
% D
% Glu:
22
0
8
15
0
15
58
0
8
0
8
8
0
8
0
% E
% Phe:
0
0
0
0
0
0
0
8
0
0
8
0
0
0
0
% F
% Gly:
0
0
8
0
8
0
0
0
8
8
0
8
8
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
8
22
0
0
0
0
0
8
15
43
0
8
15
50
% I
% Lys:
8
0
0
8
8
8
8
15
0
8
0
0
0
0
0
% K
% Leu:
0
15
0
0
8
0
0
0
29
0
8
0
0
0
15
% L
% Met:
0
0
0
0
0
0
0
15
36
0
0
0
0
0
0
% M
% Asn:
29
0
0
0
0
0
8
8
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
8
8
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
8
0
8
0
50
29
15
36
15
58
0
0
0
22
0
% S
% Thr:
22
58
0
8
8
0
0
8
0
0
8
0
0
0
15
% T
% Val:
0
8
58
8
0
0
0
0
0
8
15
0
0
0
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
8
0
0
15
72
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _