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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ATP5C1
All Species:
41.21
Human Site:
S248
Identified Species:
69.74
UniProt:
P36542
Number Species:
13
Phosphosite Substitution
Charge Score:
0.15
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P36542
NP_005165.1
298
32996
S248
S
L
K
E
S
T
T
S
E
Q
S
A
R
M
T
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001108136
297
32947
S248
S
L
K
E
S
S
T
S
E
Q
S
A
R
M
T
Dog
Lupus familis
XP_535193
298
33035
S248
S
L
K
E
S
T
T
S
E
Q
S
A
R
M
T
Cat
Felis silvestris
Mouse
Mus musculus
Q91VR2
298
32867
S248
S
L
K
E
S
T
T
S
E
Q
S
A
R
M
T
Rat
Rattus norvegicus
P35435
273
30172
E224
L
K
E
S
T
T
S
E
Q
S
A
R
M
T
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_417296
294
32705
S244
S
L
K
E
S
T
T
S
E
Q
S
A
R
M
T
Frog
Xenopus laevis
NP_001084748
294
32498
S245
T
L
K
E
S
T
T
S
E
Q
S
A
R
M
T
Zebra Danio
Brachydanio rerio
NP_956335
292
32116
S243
G
L
K
E
S
T
T
S
E
Q
S
A
R
M
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
O01666
297
32853
S247
T
M
K
E
G
A
C
S
E
Q
S
S
R
M
T
Honey Bee
Apis mellifera
XP_625078
296
32808
S246
S
M
K
E
G
A
C
S
E
Q
S
S
R
M
T
Nematode Worm
Caenorhab. elegans
NP_500214
299
32364
S250
G
M
K
E
S
A
T
S
E
Q
S
S
R
M
T
Sea Urchin
Strong. purpuratus
XP_784312
273
30282
E224
M
M
D
A
N
C
S
E
Q
S
S
R
M
T
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q96250
325
35429
S272
A
V
L
E
N
A
C
S
E
M
G
A
R
M
S
Baker's Yeast
Sacchar. cerevisiae
P38077
311
34332
A261
A
M
A
Q
G
Y
A
A
E
I
S
A
R
R
N
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
97.9
95.6
N.A.
91.2
83.5
N.A.
N.A.
81.8
80.1
77.8
N.A.
55.7
54
55.5
52.6
Protein Similarity:
100
N.A.
99.3
98.6
N.A.
97.6
89.9
N.A.
N.A.
91.6
90.9
88.9
N.A.
74.1
74.5
73.5
71.8
P-Site Identity:
100
N.A.
93.3
100
N.A.
100
6.6
N.A.
N.A.
100
93.3
93.3
N.A.
60
66.6
73.3
6.6
P-Site Similarity:
100
N.A.
100
100
N.A.
100
40
N.A.
N.A.
100
100
93.3
N.A.
80
80
86.6
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
35
37.9
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
56
60.4
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
40
26.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
66.6
53.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
15
0
8
8
0
29
8
8
0
0
8
65
0
0
15
% A
% Cys:
0
0
0
0
0
8
22
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
8
79
0
0
0
15
86
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
15
0
0
0
22
0
0
0
0
0
8
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% I
% Lys:
0
8
72
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
8
50
8
0
0
0
0
0
0
0
0
0
0
0
0
% L
% Met:
8
36
0
0
0
0
0
0
0
8
0
0
15
79
0
% M
% Asn:
0
0
0
0
15
0
0
0
0
0
0
0
0
0
8
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
8
0
0
0
0
15
72
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
15
86
8
0
% R
% Ser:
43
0
0
8
58
8
15
79
0
15
86
22
0
0
8
% S
% Thr:
15
0
0
0
8
50
58
0
0
0
0
0
0
15
72
% T
% Val:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _