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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ATP5C1
All Species:
37.88
Human Site:
Y178
Identified Species:
64.1
UniProt:
P36542
Number Species:
13
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P36542
NP_005165.1
298
32996
Y178
L
E
L
L
N
S
G
Y
E
F
D
E
G
S
I
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001108136
297
32947
Y178
L
E
L
L
N
S
G
Y
E
F
D
E
G
S
I
Dog
Lupus familis
XP_535193
298
33035
Y178
L
E
L
L
N
S
G
Y
E
F
D
E
G
S
I
Cat
Felis silvestris
Mouse
Mus musculus
Q91VR2
298
32867
Y178
L
E
L
L
N
S
G
Y
E
F
D
E
G
S
I
Rat
Rattus norvegicus
P35435
273
30172
E154
E
L
L
N
S
G
Y
E
F
D
E
G
S
I
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_417296
294
32705
Y174
S
E
L
L
N
S
G
Y
E
F
D
E
G
S
V
Frog
Xenopus laevis
NP_001084748
294
32498
Y175
S
E
L
L
N
C
G
Y
E
F
D
Q
G
S
V
Zebra Danio
Brachydanio rerio
NP_956335
292
32116
Y173
T
E
L
L
N
S
G
Y
E
F
D
Q
G
S
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
O01666
297
32853
Y177
N
E
V
L
Q
T
G
Y
D
Y
T
E
G
K
I
Honey Bee
Apis mellifera
XP_625078
296
32808
Y176
I
E
I
M
N
S
G
Y
S
F
G
S
G
R
I
Nematode Worm
Caenorhab. elegans
NP_500214
299
32364
Y180
K
A
I
L
D
S
G
Y
D
F
E
T
G
T
I
Sea Urchin
Strong. purpuratus
XP_784312
273
30282
E154
A
I
L
D
S
G
Y
E
F
D
T
A
E
V
I
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q96250
325
35429
K202
A
L
R
I
V
Y
N
K
F
H
S
V
V
A
F
Baker's Yeast
Sacchar. cerevisiae
P38077
311
34332
T191
L
S
V
M
K
A
G
T
Y
P
K
I
S
I
F
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
97.9
95.6
N.A.
91.2
83.5
N.A.
N.A.
81.8
80.1
77.8
N.A.
55.7
54
55.5
52.6
Protein Similarity:
100
N.A.
99.3
98.6
N.A.
97.6
89.9
N.A.
N.A.
91.6
90.9
88.9
N.A.
74.1
74.5
73.5
71.8
P-Site Identity:
100
N.A.
100
100
N.A.
100
13.3
N.A.
N.A.
86.6
73.3
86.6
N.A.
46.6
53.3
46.6
13.3
P-Site Similarity:
100
N.A.
100
100
N.A.
100
26.6
N.A.
N.A.
93.3
86.6
93.3
N.A.
73.3
73.3
80
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
35
37.9
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
56
60.4
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
15
8
0
0
0
8
0
0
0
0
0
8
0
8
0
% A
% Cys:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
8
8
0
0
0
15
15
50
0
0
0
0
% D
% Glu:
8
65
0
0
0
0
0
15
50
0
15
43
8
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
22
65
0
0
0
0
15
% F
% Gly:
0
0
0
0
0
15
79
0
0
0
8
8
72
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% H
% Ile:
8
8
15
8
0
0
0
0
0
0
0
8
0
15
72
% I
% Lys:
8
0
0
0
8
0
0
8
0
0
8
0
0
8
0
% K
% Leu:
36
15
65
65
0
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
15
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
8
0
0
8
58
0
8
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% P
% Gln:
0
0
0
0
8
0
0
0
0
0
0
15
0
0
0
% Q
% Arg:
0
0
8
0
0
0
0
0
0
0
0
0
0
8
0
% R
% Ser:
15
8
0
0
15
58
0
0
8
0
8
8
15
50
0
% S
% Thr:
8
0
0
0
0
8
0
8
0
0
15
8
0
8
0
% T
% Val:
0
0
15
0
8
0
0
0
0
0
0
8
8
8
15
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
8
15
72
8
8
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _