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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ATP5C1
All Species:
36.97
Human Site:
Y218
Identified Species:
62.56
UniProt:
P36542
Number Species:
13
Phosphosite Substitution
Charge Score:
0.23
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P36542
NP_005165.1
298
32996
Y218
S
A
D
S
M
S
I
Y
D
D
I
D
A
D
V
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001108136
297
32947
Y218
S
A
E
S
M
S
I
Y
D
D
I
D
A
D
V
Dog
Lupus familis
XP_535193
298
33035
Y218
S
A
E
S
M
S
I
Y
D
D
I
D
A
D
V
Cat
Felis silvestris
Mouse
Mus musculus
Q91VR2
298
32867
Y218
T
A
E
T
M
S
I
Y
D
D
I
D
A
D
V
Rat
Rattus norvegicus
P35435
273
30172
D194
A
E
N
M
S
I
Y
D
D
I
D
A
D
V
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_417296
294
32705
Y214
G
S
E
S
L
S
I
Y
D
D
I
D
A
D
V
Frog
Xenopus laevis
NP_001084748
294
32498
Y215
S
S
E
S
I
S
V
Y
D
D
I
D
A
D
V
Zebra Danio
Brachydanio rerio
NP_956335
292
32116
Y213
S
S
E
N
M
G
I
Y
D
D
I
D
A
D
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
O01666
297
32853
Y217
K
S
E
K
L
A
V
Y
D
S
L
D
S
D
V
Honey Bee
Apis mellifera
XP_625078
296
32808
Y216
S
A
P
K
L
S
L
Y
D
S
L
D
E
N
V
Nematode Worm
Caenorhab. elegans
NP_500214
299
32364
Y220
A
K
E
A
L
S
T
Y
D
S
V
D
D
D
V
Sea Urchin
Strong. purpuratus
XP_784312
273
30282
D194
A
E
K
M
S
V
Y
D
D
I
D
A
D
I
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q96250
325
35429
G242
L
D
S
Y
E
I
E
G
G
E
T
K
G
E
I
Baker's Yeast
Sacchar. cerevisiae
P38077
311
34332
E231
S
P
S
F
G
K
F
E
I
D
T
D
A
N
V
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
97.9
95.6
N.A.
91.2
83.5
N.A.
N.A.
81.8
80.1
77.8
N.A.
55.7
54
55.5
52.6
Protein Similarity:
100
N.A.
99.3
98.6
N.A.
97.6
89.9
N.A.
N.A.
91.6
90.9
88.9
N.A.
74.1
74.5
73.5
71.8
P-Site Identity:
100
N.A.
93.3
93.3
N.A.
80
6.6
N.A.
N.A.
73.3
73.3
73.3
N.A.
33.3
46.6
40
6.6
P-Site Similarity:
100
N.A.
100
100
N.A.
100
26.6
N.A.
N.A.
93.3
100
93.3
N.A.
80
73.3
73.3
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
35
37.9
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
56
60.4
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
33.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
40
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
22
36
0
8
0
8
0
0
0
0
0
15
58
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
8
8
0
0
0
0
15
86
58
15
79
22
65
0
% D
% Glu:
0
15
58
0
8
0
8
8
0
8
0
0
8
8
0
% E
% Phe:
0
0
0
8
0
0
8
0
0
0
0
0
0
0
0
% F
% Gly:
8
0
0
0
8
8
0
8
8
0
0
0
8
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
8
15
43
0
8
15
50
0
0
8
8
% I
% Lys:
8
8
8
15
0
8
0
0
0
0
0
8
0
0
0
% K
% Leu:
8
0
0
0
29
0
8
0
0
0
15
0
0
0
15
% L
% Met:
0
0
0
15
36
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
8
8
0
0
0
0
0
0
0
0
0
15
0
% N
% Pro:
0
8
8
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
50
29
15
36
15
58
0
0
0
22
0
0
8
0
0
% S
% Thr:
8
0
0
8
0
0
8
0
0
0
15
0
0
0
0
% T
% Val:
0
0
0
0
0
8
15
0
0
0
8
0
0
8
79
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
8
0
0
15
72
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _