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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ATP5C1
All Species:
13.94
Human Site:
Y77
Identified Species:
23.59
UniProt:
P36542
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.15
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P36542
NP_005165.1
298
32996
Y77
G
L
G
S
L
A
L
Y
E
K
A
D
I
K
G
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001108136
297
32947
Y77
G
L
G
S
L
A
L
Y
E
K
A
D
I
K
V
Dog
Lupus familis
XP_535193
298
33035
Y77
G
V
G
S
L
A
L
Y
E
K
A
D
I
K
V
Cat
Felis silvestris
Mouse
Mus musculus
Q91VR2
298
32867
Y77
G
T
G
S
L
A
L
Y
E
K
A
D
I
K
A
Rat
Rattus norvegicus
P35435
273
30172
K64
I
K
G
P
E
D
K
K
K
H
L
I
I
G
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_417296
294
32705
I78
A
L
Y
E
K
A
E
I
K
A
P
E
D
K
K
Frog
Xenopus laevis
NP_001084748
294
32498
A77
S
L
A
L
Y
E
K
A
E
I
K
A
P
E
D
Zebra Danio
Brachydanio rerio
NP_956335
292
32116
I77
A
L
Y
E
K
A
E
I
K
A
P
E
D
K
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
O01666
297
32853
F78
G
I
G
A
Q
Q
F
F
E
K
T
E
I
Q
P
Honey Bee
Apis mellifera
XP_625078
296
32808
A78
T
K
I
F
Y
E
Q
A
E
I
Q
A
P
P
E
Nematode Worm
Caenorhab. elegans
NP_500214
299
32364
F77
G
V
G
A
K
T
F
F
D
N
I
D
P
V
V
Sea Urchin
Strong. purpuratus
XP_784312
273
30282
K64
E
I
E
P
P
M
E
K
E
N
H
L
V
I
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q96250
325
35429
L94
W
Q
P
F
T
A
L
L
G
D
N
P
S
I
D
Baker's Yeast
Sacchar. cerevisiae
P38077
311
34332
Y85
D
E
A
E
Q
L
F
Y
K
N
A
E
T
K
N
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
97.9
95.6
N.A.
91.2
83.5
N.A.
N.A.
81.8
80.1
77.8
N.A.
55.7
54
55.5
52.6
Protein Similarity:
100
N.A.
99.3
98.6
N.A.
97.6
89.9
N.A.
N.A.
91.6
90.9
88.9
N.A.
74.1
74.5
73.5
71.8
P-Site Identity:
100
N.A.
93.3
86.6
N.A.
86.6
13.3
N.A.
N.A.
20
13.3
20
N.A.
33.3
6.6
20
6.6
P-Site Similarity:
100
N.A.
93.3
93.3
N.A.
86.6
20
N.A.
N.A.
33.3
20
33.3
N.A.
66.6
6.6
46.6
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
35
37.9
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
56
60.4
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
20
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
15
0
15
15
0
50
0
15
0
15
36
15
0
0
15
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
0
0
0
0
8
0
0
8
8
0
36
15
0
15
% D
% Glu:
8
8
8
22
8
15
22
0
58
0
0
29
0
8
8
% E
% Phe:
0
0
0
15
0
0
22
15
0
0
0
0
0
0
0
% F
% Gly:
43
0
50
0
0
0
0
0
8
0
0
0
0
8
8
% G
% His:
0
0
0
0
0
0
0
0
0
8
8
0
0
0
0
% H
% Ile:
8
15
8
0
0
0
0
15
0
15
8
8
43
15
0
% I
% Lys:
0
15
0
0
22
0
15
15
29
36
8
0
0
50
8
% K
% Leu:
0
36
0
8
29
8
36
8
0
0
8
8
0
0
0
% L
% Met:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
22
8
0
0
0
15
% N
% Pro:
0
0
8
15
8
0
0
0
0
0
15
8
22
8
8
% P
% Gln:
0
8
0
0
15
8
8
0
0
0
8
0
0
8
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
8
0
0
29
0
0
0
0
0
0
0
0
8
0
0
% S
% Thr:
8
8
0
0
8
8
0
0
0
0
8
0
8
0
0
% T
% Val:
0
15
0
0
0
0
0
0
0
0
0
0
8
8
29
% V
% Trp:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
15
0
15
0
0
36
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _