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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ATP6V1E1 All Species: 45.45
Human Site: Y56 Identified Species: 76.92
UniProt: P36543 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P36543 NP_001687.1 226 26145 Y56 Q R L K I M E Y Y E K K E K Q
Chimpanzee Pan troglodytes XP_001163440 227 26153 Y57 Q R L K I M E Y Y E K K E K Q
Rhesus Macaque Macaca mulatta XP_001113068 226 26042 Y56 Q R L K I M E Y Y E K K E K Q
Dog Lupus familis XP_534937 226 26155 Y56 Q R L K I M E Y Y E K K E K Q
Cat Felis silvestris
Mouse Mus musculus P50518 226 26139 Y56 Q R L K I M E Y Y E K K E K Q
Rat Rattus norvegicus Q6PCU2 226 26110 Y56 Q R L K I M E Y Y E K K E K Q
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus NP_001006246 226 26100 Y56 Q R L K I M E Y Y E K K E K Q
Frog Xenopus laevis NP_001079767 226 25885 Y56 Q R L K I M E Y Y E K K E K Q
Zebra Danio Brachydanio rerio NP_775361 226 25892 Y56 Q R L K I M E Y Y E K K E K Q
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P54611 226 26064 Y56 Q R L K I M E Y Y E K K E K Q
Honey Bee Apis mellifera XP_625098 226 26115 Y56 Q R L K I M E Y Y E K K E K Q
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q39258 230 26041 D54 E K K K I R Q D Y E K K E K Q
Baker's Yeast Sacchar. cerevisiae P22203 233 26453 N61 E T N N I D G N F K S K L K K
Red Bread Mold Neurospora crassa Q01278 230 25730 A60 E T D A I D S A Y A K K F K Q
Conservation
Percent
Protein Identity: 100 85.9 77.4 99.1 N.A. 98.6 98.6 N.A. N.A. 88 83.1 77.4 N.A. 63.2 63.2 N.A. N.A.
Protein Similarity: 100 88.5 87.6 99.5 N.A. 99.5 99.1 N.A. N.A. 95.5 93.8 90.2 N.A. 81.8 81.4 N.A. N.A.
P-Site Identity: 100 100 100 100 N.A. 100 100 N.A. N.A. 100 100 100 N.A. 100 100 N.A. N.A.
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. N.A. 100 100 100 N.A. 100 100 N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. 40.8 33 42.1
Protein Similarity: N.A. N.A. N.A. 62.6 58.3 60
P-Site Identity: N.A. N.A. N.A. 60 20 40
P-Site Similarity: N.A. N.A. N.A. 80 46.6 46.6
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 8 0 0 0 8 0 8 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 8 0 0 15 0 8 0 0 0 0 0 0 0 % D
% Glu: 22 0 0 0 0 0 79 0 0 86 0 0 86 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 8 0 0 0 8 0 0 % F
% Gly: 0 0 0 0 0 0 8 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 8 8 86 0 0 0 0 0 8 93 100 0 100 8 % K
% Leu: 0 0 79 0 0 0 0 0 0 0 0 0 8 0 0 % L
% Met: 0 0 0 0 0 79 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 8 8 0 0 0 8 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 79 0 0 0 0 0 8 0 0 0 0 0 0 0 93 % Q
% Arg: 0 79 0 0 0 8 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 0 0 0 0 0 8 0 0 0 8 0 0 0 0 % S
% Thr: 0 15 0 0 0 0 0 0 0 0 0 0 0 0 0 % T
% Val: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 79 93 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _