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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CHRNA7 All Species: 23.94
Human Site: S365 Identified Species: 47.88
UniProt: P36544 Number Species: 11
    Phosphosite Substitution
    Charge Score: -0.09
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P36544 NP_000737.1 502 56449 S365 Q H K Q R R C S L A S V E M S
Chimpanzee Pan troglodytes Q5IS52 529 59755 S400 L H L K L S P S Y H W L E S N
Rhesus Macaque Macaca mulatta Q866A2 502 56411 S365 Q H K Q R R C S L A S V E M S
Dog Lupus familis XP_545813 499 56257 S362 Q H K Q R R C S L A S V E M S
Cat Felis silvestris
Mouse Mus musculus P49582 502 56613 S365 Q H K P R R C S L A S V E L S
Rat Rattus norvegicus Q05941 502 56484 S365 Q H K P R R C S L A S V E L S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001517489 314 34257 M193 A P A A N G N M L Y I G F R G
Chicken Gallus gallus P22770 502 56928 S365 Q H K Q R R C S L S S M E M N
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_957513 509 58038 L366 N K Q P R S S L S S V D L N I
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P17644 576 65488 L406 K T K F G Q A L M D E M Q M N
Honey Bee Apis mellifera NP_001073564 529 59946 L390 K I T K K T I L G G N R R A K
Nematode Worm Caenorhab. elegans P48180 498 57150 R373 R H S E S L I R N I K D N E H
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 39.3 99 96.4 N.A. 93.4 93.4 N.A. 54.5 89.8 N.A. 75.2 N.A. 36.2 46.5 45.2 N.A.
Protein Similarity: 100 55.7 99.5 98 N.A. 97 97 N.A. 57.5 93.4 N.A. 85.8 N.A. 56 63.1 61.3 N.A.
P-Site Identity: 100 20 100 100 N.A. 86.6 86.6 N.A. 6.6 80 N.A. 6.6 N.A. 13.3 0 6.6 N.A.
P-Site Similarity: 100 40 100 100 N.A. 93.3 93.3 N.A. 6.6 100 N.A. 20 N.A. 53.3 26.6 20 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 9 0 9 9 0 0 9 0 0 42 0 0 0 9 0 % A
% Cys: 0 0 0 0 0 0 50 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 9 0 17 0 0 0 % D
% Glu: 0 0 0 9 0 0 0 0 0 0 9 0 59 9 0 % E
% Phe: 0 0 0 9 0 0 0 0 0 0 0 0 9 0 0 % F
% Gly: 0 0 0 0 9 9 0 0 9 9 0 9 0 0 9 % G
% His: 0 67 0 0 0 0 0 0 0 9 0 0 0 0 9 % H
% Ile: 0 9 0 0 0 0 17 0 0 9 9 0 0 0 9 % I
% Lys: 17 9 59 17 9 0 0 0 0 0 9 0 0 0 9 % K
% Leu: 9 0 9 0 9 9 0 25 59 0 0 9 9 17 0 % L
% Met: 0 0 0 0 0 0 0 9 9 0 0 17 0 42 0 % M
% Asn: 9 0 0 0 9 0 9 0 9 0 9 0 9 9 25 % N
% Pro: 0 9 0 25 0 0 9 0 0 0 0 0 0 0 0 % P
% Gln: 50 0 9 34 0 9 0 0 0 0 0 0 9 0 0 % Q
% Arg: 9 0 0 0 59 50 0 9 0 0 0 9 9 9 0 % R
% Ser: 0 0 9 0 9 17 9 59 9 17 50 0 0 9 42 % S
% Thr: 0 9 9 0 0 9 0 0 0 0 0 0 0 0 0 % T
% Val: 0 0 0 0 0 0 0 0 0 0 9 42 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 9 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 9 9 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _