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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CHRNA7
All Species:
26.06
Human Site:
Y386
Identified Species:
52.12
UniProt:
P36544
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P36544
NP_000737.1
502
56449
Y386
A
S
N
G
N
L
L
Y
I
G
F
R
G
L
D
Chimpanzee
Pan troglodytes
Q5IS52
529
59755
D421
E
V
V
V
E
E
E
D
R
W
A
C
A
G
H
Rhesus Macaque
Macaca mulatta
Q866A2
502
56411
Y386
A
S
N
G
N
L
L
Y
I
G
F
R
G
L
D
Dog
Lupus familis
XP_545813
499
56257
Y383
T
T
N
G
N
L
L
Y
I
G
F
R
G
L
D
Cat
Felis silvestris
Mouse
Mus musculus
P49582
502
56613
Y386
T
S
N
G
N
L
L
Y
I
G
F
R
G
L
E
Rat
Rattus norvegicus
Q05941
502
56484
Y386
T
S
N
G
N
L
L
Y
I
G
F
R
G
L
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517489
314
34257
V214
S
P
T
P
D
S
G
V
I
C
G
R
L
A
C
Chicken
Gallus gallus
P22770
502
56928
Y386
C
S
N
G
N
M
L
Y
I
G
F
R
G
L
D
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_957513
509
58038
Y387
S
T
N
G
N
L
L
Y
I
G
F
R
G
M
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P17644
576
65488
G427
D
S
L
R
R
M
Q
G
R
V
G
A
G
G
C
Honey Bee
Apis mellifera
NP_001073564
529
59946
A411
K
S
S
K
S
L
L
A
N
V
L
D
I
D
D
Nematode Worm
Caenorhab. elegans
P48180
498
57150
L394
S
F
D
A
D
C
R
L
N
Q
Y
I
M
T
Q
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
39.3
99
96.4
N.A.
93.4
93.4
N.A.
54.5
89.8
N.A.
75.2
N.A.
36.2
46.5
45.2
N.A.
Protein Similarity:
100
55.7
99.5
98
N.A.
97
97
N.A.
57.5
93.4
N.A.
85.8
N.A.
56
63.1
61.3
N.A.
P-Site Identity:
100
0
100
86.6
N.A.
86.6
86.6
N.A.
13.3
86.6
N.A.
80
N.A.
13.3
26.6
0
N.A.
P-Site Similarity:
100
0
100
93.3
N.A.
93.3
93.3
N.A.
26.6
93.3
N.A.
100
N.A.
20
40
26.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
17
0
0
9
0
0
0
9
0
0
9
9
9
9
0
% A
% Cys:
9
0
0
0
0
9
0
0
0
9
0
9
0
0
17
% C
% Asp:
9
0
9
0
17
0
0
9
0
0
0
9
0
9
50
% D
% Glu:
9
0
0
0
9
9
9
0
0
0
0
0
0
0
17
% E
% Phe:
0
9
0
0
0
0
0
0
0
0
59
0
0
0
0
% F
% Gly:
0
0
0
59
0
0
9
9
0
59
17
0
67
17
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
9
% H
% Ile:
0
0
0
0
0
0
0
0
67
0
0
9
9
0
0
% I
% Lys:
9
0
0
9
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
9
0
0
59
67
9
0
0
9
0
9
50
0
% L
% Met:
0
0
0
0
0
17
0
0
0
0
0
0
9
9
0
% M
% Asn:
0
0
59
0
59
0
0
0
17
0
0
0
0
0
0
% N
% Pro:
0
9
0
9
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
9
0
0
9
0
0
0
0
9
% Q
% Arg:
0
0
0
9
9
0
9
0
17
0
0
67
0
0
0
% R
% Ser:
25
59
9
0
9
9
0
0
0
0
0
0
0
0
0
% S
% Thr:
25
17
9
0
0
0
0
0
0
0
0
0
0
9
0
% T
% Val:
0
9
9
9
0
0
0
9
0
17
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
9
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
59
0
0
9
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _