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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CPOX All Species: 21.52
Human Site: Y312 Identified Species: 39.44
UniProt: P36551 Number Species: 12
    Phosphosite Substitution
    Charge Score: -0.17
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P36551 NP_000088.3 454 50152 Y312 D Q H G P D L Y P K F K K W C
Chimpanzee Pan troglodytes XP_516615 454 50299 Y312 D Q H G P D L Y P K F K K W C
Rhesus Macaque Macaca mulatta XP_001088605 453 50007 Y311 D Q H G P E L Y P K F K K W C
Dog Lupus familis XP_545070 303 34842 G178 Y F F I V H R G E R R G I G G
Cat Felis silvestris
Mouse Mus musculus P36552 443 49696 Y301 D Q H G P D I Y P K F K K W C
Rat Rattus norvegicus Q3B7D0 443 49260 Y301 D Q H G P D I Y P K F K K W C
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001519105 411 45703 G286 Y F F I T H R G E R R G I G G
Chicken Gallus gallus XP_416596 404 45414 G279 Y F H I K H R G E R R G I G G
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_001035183 449 50917 Y308 D K H H P K Y Y P D F K K W C
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9V3D2 390 44401 R265 D Y F R I K H R N E S R G I G
Honey Bee Apis mellifera XP_624465 356 41209 G231 Y F F I T H R G E R R G V G G
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9LR75 386 43778 H261 D D Y F Y I K H R D E R R G L
Baker's Yeast Sacchar. cerevisiae P11353 328 37693 K203 Y F Y I T H R K E T R G I G G
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.6 95.1 61.4 N.A. 79.9 79.7 N.A. 73.1 66.7 N.A. 59.4 N.A. 53.2 51.5 N.A. N.A.
Protein Similarity: 100 99.1 96.9 63.4 N.A. 87.2 87.2 N.A. 79.5 75.3 N.A. 72.9 N.A. 65.6 63.8 N.A. N.A.
P-Site Identity: 100 100 93.3 0 N.A. 93.3 93.3 N.A. 0 6.6 N.A. 66.6 N.A. 6.6 0 N.A. N.A.
P-Site Similarity: 100 100 100 6.6 N.A. 100 100 N.A. 6.6 13.3 N.A. 73.3 N.A. 20 6.6 N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. 44.9 35.9 N.A.
Protein Similarity: N.A. N.A. N.A. 57.7 46.9 N.A.
P-Site Identity: N.A. N.A. N.A. 6.6 0 N.A.
P-Site Similarity: N.A. N.A. N.A. 33.3 6.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 47 % C
% Asp: 62 8 0 0 0 31 0 0 0 16 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 8 0 0 39 8 8 0 0 0 0 % E
% Phe: 0 39 31 8 0 0 0 0 0 0 47 0 0 0 0 % F
% Gly: 0 0 0 39 0 0 0 31 0 0 0 39 8 47 47 % G
% His: 0 0 54 8 0 39 8 8 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 39 8 8 16 0 0 0 0 0 31 8 0 % I
% Lys: 0 8 0 0 8 16 8 8 0 39 0 47 47 0 0 % K
% Leu: 0 0 0 0 0 0 24 0 0 0 0 0 0 0 8 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 8 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 47 0 0 0 47 0 0 0 0 0 0 % P
% Gln: 0 39 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 8 0 0 39 8 8 31 39 16 8 0 0 % R
% Ser: 0 0 0 0 0 0 0 0 0 0 8 0 0 0 0 % S
% Thr: 0 0 0 0 24 0 0 0 0 8 0 0 0 0 0 % T
% Val: 0 0 0 0 8 0 0 0 0 0 0 0 8 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 47 0 % W
% Tyr: 39 8 16 0 8 0 8 47 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _