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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: LONP1 All Species: 25.15
Human Site: S176 Identified Species: 36.89
UniProt: P36776 Number Species: 15
    Phosphosite Substitution
    Charge Score: 0.13
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P36776 NP_004784.2 959 106489 S176 K R D D S N E S D V V E S L D
Chimpanzee Pan troglodytes XP_001143873 959 106437 S176 K R D D S N E S D V V E S L D
Rhesus Macaque Macaca mulatta XP_001088663 909 101136 S176 K R D D N N E S D V V E N L D
Dog Lupus familis XP_854391 960 106631 S177 K R D D N N E S D V V E S L D
Cat Felis silvestris
Mouse Mus musculus Q8CGK3 949 105824 S164 K R D D N N E S D V V E S L D
Rat Rattus norvegicus Q924S5 950 105774 S164 K R D D N N E S D V V E S L D
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506549 791 89382 P97 K P R R K P K P A V K S A E E
Chicken Gallus gallus XP_001232112 790 89040 L96 M Q D L G D K L R M I V M G H
Frog Xenopus laevis Q2TAF8 856 94553 K140 L S S K E E F K E A L G D L S
Zebra Danio Brachydanio rerio Q5PQY6 840 92202 D140 Y T E G D P A D G E L G E L S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_649133 1006 112875 E145 L K K T D G E E E L I T N L N
Honey Bee Apis mellifera XP_392970 995 112847 A164 K K L E E N E A E I V Q N L D
Nematode Worm Caenorhab. elegans O44952 971 108188 E142 K R D D E N K E E T I T S L S
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays P93648 964 105641 L157 S A K S I D D L K G K D L L K
Rice Oryza sativa
Thale Cress Arabidopsis thaliana P93655 940 103912 A142 R Q A P Y A G A F L L K D D P
Baker's Yeast Sacchar. cerevisiae P36775 1133 127093 T234 L K N S E E D T D V I T D K N
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.5 86.6 93.7 N.A. 87.4 88.6 N.A. 71.6 73.8 32.2 32.7 N.A. 59.4 58.9 51.5 N.A.
Protein Similarity: 100 99.6 89 96 N.A. 92 92.8 N.A. 77 78.5 50.8 52.3 N.A. 73.3 74.9 67.2 N.A.
P-Site Identity: 100 100 86.6 93.3 N.A. 93.3 93.3 N.A. 13.3 6.6 6.6 6.6 N.A. 13.3 40 46.6 N.A.
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. 33.3 40 20 20 N.A. 53.3 86.6 66.6 N.A.
Percent
Protein Identity: N.A. 48.7 N.A. 48.1 39.1 N.A.
Protein Similarity: N.A. 65.8 N.A. 65.4 57.1 N.A.
P-Site Identity: N.A. 6.6 N.A. 0 13.3 N.A.
P-Site Similarity: N.A. 26.6 N.A. 40 53.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 7 7 0 0 7 7 13 7 7 0 0 7 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 50 44 13 13 13 7 44 0 0 7 19 7 44 % D
% Glu: 0 0 7 7 25 13 50 13 25 7 0 38 7 7 7 % E
% Phe: 0 0 0 0 0 0 7 0 7 0 0 0 0 0 0 % F
% Gly: 0 0 0 7 7 7 7 0 7 7 0 13 0 7 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 7 % H
% Ile: 0 0 0 0 7 0 0 0 0 7 25 0 0 0 0 % I
% Lys: 57 19 13 7 7 0 19 7 7 0 13 7 0 7 7 % K
% Leu: 19 0 7 7 0 0 0 13 0 13 19 0 7 75 0 % L
% Met: 7 0 0 0 0 0 0 0 0 7 0 0 7 0 0 % M
% Asn: 0 0 7 0 25 50 0 0 0 0 0 0 19 0 13 % N
% Pro: 0 7 0 7 0 13 0 7 0 0 0 0 0 0 7 % P
% Gln: 0 13 0 0 0 0 0 0 0 0 0 7 0 0 0 % Q
% Arg: 7 44 7 7 0 0 0 0 7 0 0 0 0 0 0 % R
% Ser: 7 7 7 13 13 0 0 38 0 0 0 7 38 0 19 % S
% Thr: 0 7 0 7 0 0 0 7 0 7 0 19 0 0 0 % T
% Val: 0 0 0 0 0 0 0 0 0 50 44 7 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 7 0 0 0 7 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _