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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
LONP1
All Species:
21.21
Human Site:
S181
Identified Species:
31.11
UniProt:
P36776
Number Species:
15
Phosphosite Substitution
Charge Score:
0.27
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P36776
NP_004784.2
959
106489
S181
N
E
S
D
V
V
E
S
L
D
E
I
Y
H
T
Chimpanzee
Pan troglodytes
XP_001143873
959
106437
S181
N
E
S
D
V
V
E
S
L
D
E
I
Y
H
T
Rhesus Macaque
Macaca mulatta
XP_001088663
909
101136
N181
N
E
S
D
V
V
E
N
L
D
E
I
Y
H
T
Dog
Lupus familis
XP_854391
960
106631
S182
N
E
S
D
V
V
E
S
L
D
E
V
Y
H
T
Cat
Felis silvestris
Mouse
Mus musculus
Q8CGK3
949
105824
S169
N
E
S
D
V
V
E
S
L
D
E
I
Y
H
T
Rat
Rattus norvegicus
Q924S5
950
105774
S169
N
E
S
D
V
V
E
S
L
D
E
I
Y
H
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506549
791
89382
A102
P
K
P
A
V
K
S
A
E
E
R
Q
V
T
Q
Chicken
Gallus gallus
XP_001232112
790
89040
M101
D
K
L
R
M
I
V
M
G
H
R
R
I
R
I
Frog
Xenopus laevis
Q2TAF8
856
94553
D145
E
F
K
E
A
L
G
D
L
S
E
Q
F
Y
K
Zebra Danio
Brachydanio rerio
Q5PQY6
840
92202
E145
P
A
D
G
E
L
G
E
L
S
Q
R
F
Y
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_649133
1006
112875
N150
G
E
E
E
L
I
T
N
L
N
D
V
Y
N
L
Honey Bee
Apis mellifera
XP_392970
995
112847
N169
N
E
A
E
I
V
Q
N
L
D
D
I
Y
S
V
Nematode Worm
Caenorhab. elegans
O44952
971
108188
S147
N
K
E
E
T
I
T
S
L
S
E
V
Y
P
T
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
P93648
964
105641
L162
D
D
L
K
G
K
D
L
L
K
R
L
H
E
V
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P93655
940
103912
D147
A
G
A
F
L
L
K
D
D
P
S
A
D
S
S
Baker's Yeast
Sacchar. cerevisiae
P36775
1133
127093
D239
E
D
T
D
V
I
T
D
K
N
D
V
Y
D
V
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
86.6
93.7
N.A.
87.4
88.6
N.A.
71.6
73.8
32.2
32.7
N.A.
59.4
58.9
51.5
N.A.
Protein Similarity:
100
99.6
89
96
N.A.
92
92.8
N.A.
77
78.5
50.8
52.3
N.A.
73.3
74.9
67.2
N.A.
P-Site Identity:
100
100
93.3
93.3
N.A.
100
100
N.A.
6.6
0
13.3
6.6
N.A.
20
46.6
40
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
26.6
26.6
40
33.3
N.A.
73.3
86.6
66.6
N.A.
Percent
Protein Identity:
N.A.
48.7
N.A.
48.1
39.1
N.A.
Protein Similarity:
N.A.
65.8
N.A.
65.4
57.1
N.A.
P-Site Identity:
N.A.
6.6
N.A.
0
20
N.A.
P-Site Similarity:
N.A.
40
N.A.
33.3
60
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
7
13
7
7
0
0
7
0
0
0
7
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
13
13
7
44
0
0
7
19
7
44
19
0
7
7
0
% D
% Glu:
13
50
13
25
7
0
38
7
7
7
50
0
0
7
0
% E
% Phe:
0
7
0
7
0
0
0
0
0
0
0
0
13
0
0
% F
% Gly:
7
7
0
7
7
0
13
0
7
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
7
0
0
7
38
0
% H
% Ile:
0
0
0
0
7
25
0
0
0
0
0
38
7
0
7
% I
% Lys:
0
19
7
7
0
13
7
0
7
7
0
0
0
0
7
% K
% Leu:
0
0
13
0
13
19
0
7
75
0
0
7
0
0
7
% L
% Met:
0
0
0
0
7
0
0
7
0
0
0
0
0
0
0
% M
% Asn:
50
0
0
0
0
0
0
19
0
13
0
0
0
7
0
% N
% Pro:
13
0
7
0
0
0
0
0
0
7
0
0
0
7
0
% P
% Gln:
0
0
0
0
0
0
7
0
0
0
7
13
0
0
13
% Q
% Arg:
0
0
0
7
0
0
0
0
0
0
19
13
0
7
0
% R
% Ser:
0
0
38
0
0
0
7
38
0
19
7
0
0
13
7
% S
% Thr:
0
0
7
0
7
0
19
0
0
0
0
0
0
7
44
% T
% Val:
0
0
0
0
50
44
7
0
0
0
0
25
7
0
19
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
63
13
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _