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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
LONP1
All Species:
38.79
Human Site:
S453
Identified Species:
56.89
UniProt:
P36776
Number Species:
15
Phosphosite Substitution
Charge Score:
0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P36776
NP_004784.2
959
106489
S453
G
L
L
D
N
H
S
S
E
F
N
V
T
R
N
Chimpanzee
Pan troglodytes
XP_001143873
959
106437
S453
G
L
L
D
N
H
S
S
E
F
N
V
T
R
N
Rhesus Macaque
Macaca mulatta
XP_001088663
909
101136
E423
A
I
E
E
K
F
R
E
R
L
K
E
L
V
V
Dog
Lupus familis
XP_854391
960
106631
S454
G
L
L
D
N
H
S
S
E
F
N
V
T
R
N
Cat
Felis silvestris
Mouse
Mus musculus
Q8CGK3
949
105824
S442
A
L
L
D
N
H
S
S
E
F
N
V
T
R
N
Rat
Rattus norvegicus
Q924S5
950
105774
S443
A
L
L
D
N
H
S
S
E
F
N
V
T
R
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506549
791
89382
G309
D
E
E
L
S
K
L
G
L
L
D
N
H
S
S
Chicken
Gallus gallus
XP_001232112
790
89040
I308
E
K
E
D
K
D
A
I
E
E
K
F
R
E
R
Frog
Xenopus laevis
Q2TAF8
856
94553
L353
D
H
Y
A
M
A
K
L
K
K
R
V
L
E
Y
Zebra Danio
Brachydanio rerio
Q5PQY6
840
92202
L354
E
K
L
K
K
R
V
L
E
Y
L
A
V
R
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_649133
1006
112875
S476
N
F
L
E
S
H
S
S
E
F
N
V
T
R
N
Honey Bee
Apis mellifera
XP_392970
995
112847
S471
N
F
L
E
S
H
S
S
E
F
N
V
T
R
N
Nematode Worm
Caenorhab. elegans
O44952
971
108188
S442
Q
F
L
D
P
H
S
S
E
F
S
V
T
R
N
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
P93648
964
105641
S385
Q
L
L
E
A
S
S
S
E
F
S
V
T
R
N
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P93655
940
103912
S394
Q
L
L
E
A
S
S
S
E
F
N
V
T
R
N
Baker's Yeast
Sacchar. cerevisiae
P36775
1133
127093
S562
S
T
L
E
T
S
M
S
E
F
G
V
I
R
N
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
86.6
93.7
N.A.
87.4
88.6
N.A.
71.6
73.8
32.2
32.7
N.A.
59.4
58.9
51.5
N.A.
Protein Similarity:
100
99.6
89
96
N.A.
92
92.8
N.A.
77
78.5
50.8
52.3
N.A.
73.3
74.9
67.2
N.A.
P-Site Identity:
100
100
0
100
N.A.
93.3
93.3
N.A.
0
13.3
6.6
20
N.A.
73.3
73.3
73.3
N.A.
P-Site Similarity:
100
100
13.3
100
N.A.
93.3
93.3
N.A.
20
20
13.3
26.6
N.A.
86.6
86.6
80
N.A.
Percent
Protein Identity:
N.A.
48.7
N.A.
48.1
39.1
N.A.
Protein Similarity:
N.A.
65.8
N.A.
65.4
57.1
N.A.
P-Site Identity:
N.A.
66.6
N.A.
73.3
46.6
N.A.
P-Site Similarity:
N.A.
80
N.A.
80
53.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
19
0
0
7
13
7
7
0
0
0
0
7
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
13
0
0
44
0
7
0
0
0
0
7
0
0
0
0
% D
% Glu:
13
7
19
38
0
0
0
7
82
7
0
7
0
13
0
% E
% Phe:
0
19
0
0
0
7
0
0
0
69
0
7
0
0
0
% F
% Gly:
19
0
0
0
0
0
0
7
0
0
7
0
0
0
0
% G
% His:
0
7
0
0
0
50
0
0
0
0
0
0
7
0
0
% H
% Ile:
0
7
0
0
0
0
0
7
0
0
0
0
7
0
0
% I
% Lys:
0
13
0
7
19
7
7
0
7
7
13
0
0
0
0
% K
% Leu:
0
44
75
7
0
0
7
13
7
13
7
0
13
0
0
% L
% Met:
0
0
0
0
7
0
7
0
0
0
0
0
0
0
0
% M
% Asn:
13
0
0
0
32
0
0
0
0
0
50
7
0
0
69
% N
% Pro:
0
0
0
0
7
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
19
0
0
0
0
0
0
0
0
0
0
0
0
0
7
% Q
% Arg:
0
0
0
0
0
7
7
0
7
0
7
0
7
75
7
% R
% Ser:
7
0
0
0
19
19
63
69
0
0
13
0
0
7
7
% S
% Thr:
0
7
0
0
7
0
0
0
0
0
0
0
63
0
0
% T
% Val:
0
0
0
0
0
0
7
0
0
0
0
75
7
7
7
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
7
0
0
0
0
0
0
7
0
0
0
0
7
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _