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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: LONP1 All Species: 40
Human Site: T849 Identified Species: 58.67
UniProt: P36776 Number Species: 15
    Phosphosite Substitution
    Charge Score: -0.07
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P36776 NP_004784.2 959 106489 T849 L H V P E G A T P K D G P S A
Chimpanzee Pan troglodytes XP_001143873 959 106437 T849 L H V P E G A T P K D G P S A
Rhesus Macaque Macaca mulatta XP_001088663 909 101136 K812 G Q L G E V M K E S A R I A Y
Dog Lupus familis XP_854391 960 106631 T850 L H V P E G A T P K D G P S A
Cat Felis silvestris
Mouse Mus musculus Q8CGK3 949 105824 T838 L H V P E G A T P K D G P S A
Rat Rattus norvegicus Q924S5 950 105774 T839 L H V P E G A T P K D G P S A
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506549 791 89382 W694 Q K X X X X X W I L N N Q V H
Chicken Gallus gallus XP_001232112 790 89040 Q693 G S L E V T G Q L G D V M K E
Frog Xenopus laevis Q2TAF8 856 94553 V741 L H F P A G A V T K D G P S A
Zebra Danio Brachydanio rerio Q5PQY6 840 92202 L743 I V T C L A S L L S G R L V R
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_649133 1006 112875 T874 L H V P E G A T P K D G P S A
Honey Bee Apis mellifera XP_392970 995 112847 G868 E G A T P K D G P S A G I T I
Nematode Worm Caenorhab. elegans O44952 971 108188 T872 I H V P E G A T P K D G P S A
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays P93648 964 105641 T857 L H V P A G S T P K D G P S A
Rice Oryza sativa
Thale Cress Arabidopsis thaliana P93655 940 103912 T835 L H V P A G A T P K D G P S A
Baker's Yeast Sacchar. cerevisiae P36775 1133 127093 T1009 L H C P E G A T P K D G P S A
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.5 86.6 93.7 N.A. 87.4 88.6 N.A. 71.6 73.8 32.2 32.7 N.A. 59.4 58.9 51.5 N.A.
Protein Similarity: 100 99.6 89 96 N.A. 92 92.8 N.A. 77 78.5 50.8 52.3 N.A. 73.3 74.9 67.2 N.A.
P-Site Identity: 100 100 6.6 100 N.A. 100 100 N.A. 0 6.6 73.3 0 N.A. 100 13.3 93.3 N.A.
P-Site Similarity: 100 100 20 100 N.A. 100 100 N.A. 6.6 13.3 73.3 13.3 N.A. 100 20 100 N.A.
Percent
Protein Identity: N.A. 48.7 N.A. 48.1 39.1 N.A.
Protein Similarity: N.A. 65.8 N.A. 65.4 57.1 N.A.
P-Site Identity: N.A. 86.6 N.A. 93.3 93.3 N.A.
P-Site Similarity: N.A. 93.3 N.A. 93.3 93.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 7 0 19 7 63 0 0 0 13 0 0 7 69 % A
% Cys: 0 0 7 7 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 7 0 0 0 75 0 0 0 0 % D
% Glu: 7 0 0 7 57 0 0 0 7 0 0 0 0 0 7 % E
% Phe: 0 0 7 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 13 7 0 7 0 69 7 7 0 7 7 75 0 0 0 % G
% His: 0 69 0 0 0 0 0 0 0 0 0 0 0 0 7 % H
% Ile: 13 0 0 0 0 0 0 0 7 0 0 0 13 0 7 % I
% Lys: 0 7 0 0 0 7 0 7 0 69 0 0 0 7 0 % K
% Leu: 63 0 13 0 7 0 0 7 13 7 0 0 7 0 0 % L
% Met: 0 0 0 0 0 0 7 0 0 0 0 0 7 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 7 7 0 0 0 % N
% Pro: 0 0 0 69 7 0 0 0 69 0 0 0 69 0 0 % P
% Gln: 7 7 0 0 0 0 0 7 0 0 0 0 7 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 13 0 0 7 % R
% Ser: 0 7 0 0 0 0 13 0 0 19 0 0 0 69 0 % S
% Thr: 0 0 7 7 0 7 0 63 7 0 0 0 0 7 0 % T
% Val: 0 7 57 0 7 7 0 7 0 0 0 7 0 13 0 % V
% Trp: 0 0 0 0 0 0 0 7 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 7 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _