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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PPP1CC All Species: 23.94
Human Site: T307 Identified Species: 32.92
UniProt: P36873 Number Species: 16
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P36873 NP_002701.1 323 36984 T307 E K K K P N A T R P V T P P R
Chimpanzee Pan troglodytes XP_001144148 355 40088 T339 E K K K P N A T R P V T P P R
Rhesus Macaque Macaca mulatta XP_001108258 337 38500 T307 E K K K P N A T R P V T P P R
Dog Lupus familis
Cat Felis silvestris
Mouse Mus musculus P62137 330 37522 G307 D K N K G K Y G Q F S G L N P
Rat Rattus norvegicus P62138 330 37494 G307 D K N K G K Y G Q F S G L N P
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506012 354 40218 S338 E K K K P N A S R P V T P P R
Chicken Gallus gallus NP_001006190 323 36981 S307 E K K K P N A S R P V T P P R
Frog Xenopus laevis Q7SZ10 323 36919 S307 E K K K P N A S R P V T P P R
Zebra Danio Brachydanio rerio XP_700468 242 27469 N227 A A S F Q G T N V S R F T V T
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P48461 327 37351 P305 D K R R F V Y P N F G S S G R
Honey Bee Apis mellifera XP_392943 329 37410 G307 D K K K L T Y G G L N A N R P
Nematode Worm Caenorhab. elegans P48727 333 37773 G306 D K K K Y P Y G A G G V G S N
Sea Urchin Strong. purpuratus XP_791029 330 37658 Y307 D K N K K F P Y S G I G G S G
Poplar Tree Populus trichocarpa
Maize Zea mays P22198 316 35745 F290 D D T L M C S F Q I L K P A R
Rice Oryza sativa
Thale Cress Arabidopsis thaliana P48482 312 35513 C297 S V D E S L M C S F Q I L K P
Baker's Yeast Sacchar. cerevisiae P32598 312 35889 F292 D E S L L C S F Q I L K P A Q
Red Bread Mold Neurospora crassa Q9UW86 308 35549 F293 D E S L L C S F Q I L K P A E
Conservation
Percent
Protein Identity: 100 90.9 94 N.A. N.A. 91.8 92.1 N.A. 88.1 99 99 58.2 N.A. 88.6 91.4 89.4 88.4
Protein Similarity: 100 90.9 94.9 N.A. N.A. 94.2 94.2 N.A. 89.5 99.6 100 61.2 N.A. 93.5 94.2 93.6 93.6
P-Site Identity: 100 100 100 N.A. N.A. 13.3 13.3 N.A. 93.3 93.3 93.3 0 N.A. 13.3 20 20 13.3
P-Site Similarity: 100 100 100 N.A. N.A. 26.6 26.6 N.A. 100 100 100 0 N.A. 40 26.6 26.6 26.6
Percent
Protein Identity: N.A. 73 N.A. 74.9 81.7 82.3
Protein Similarity: N.A. 83.9 N.A. 84.2 89.4 89.7
P-Site Identity: N.A. 13.3 N.A. 0 6.6 6.6
P-Site Similarity: N.A. 40 N.A. 6.6 46.6 40
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 6 6 0 0 0 0 36 0 6 0 0 6 0 18 0 % A
% Cys: 0 0 0 0 0 18 0 6 0 0 0 0 0 0 0 % C
% Asp: 53 6 6 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 36 12 0 6 0 0 0 0 0 0 0 0 0 0 6 % E
% Phe: 0 0 0 6 6 6 0 18 0 24 0 6 0 0 0 % F
% Gly: 0 0 0 0 12 6 0 24 6 12 12 18 12 6 6 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 18 6 6 0 0 0 % I
% Lys: 0 71 48 65 6 12 0 0 0 0 0 18 0 6 0 % K
% Leu: 0 0 0 18 18 6 0 0 0 6 18 0 18 0 0 % L
% Met: 0 0 0 0 6 0 6 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 18 0 0 36 0 6 6 0 6 0 6 12 6 % N
% Pro: 0 0 0 0 36 6 6 6 0 36 0 0 53 36 24 % P
% Gln: 0 0 0 0 6 0 0 0 30 0 6 0 0 0 6 % Q
% Arg: 0 0 6 6 0 0 0 0 36 0 6 0 0 6 48 % R
% Ser: 6 0 18 0 6 0 18 18 12 6 12 6 6 12 0 % S
% Thr: 0 0 6 0 0 6 6 18 0 0 0 36 6 0 6 % T
% Val: 0 6 0 0 0 6 0 0 6 0 36 6 0 6 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 6 0 30 6 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _