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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PPP1CC
All Species:
19.04
Human Site:
T318
Identified Species:
26.19
UniProt:
P36873
Number Species:
16
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P36873
NP_002701.1
323
36984
T318
T
P
P
R
G
M
I
T
K
Q
A
K
K
_
_
Chimpanzee
Pan troglodytes
XP_001144148
355
40088
T350
T
P
P
R
G
M
I
T
K
Q
A
K
K
_
_
Rhesus Macaque
Macaca mulatta
XP_001108258
337
38500
G318
T
P
P
R
V
A
S
G
L
N
P
S
I
Q
K
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
P62137
330
37522
P318
G
L
N
P
G
G
R
P
I
T
P
P
R
N
S
Rat
Rattus norvegicus
P62138
330
37494
P318
G
L
N
P
G
G
R
P
I
T
P
P
R
N
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506012
354
40218
T349
T
P
P
R
G
M
I
T
K
Q
A
K
K
_
_
Chicken
Gallus gallus
NP_001006190
323
36981
T318
T
P
P
R
S
M
I
T
K
Q
A
K
K
_
_
Frog
Xenopus laevis
Q7SZ10
323
36919
T318
T
P
P
R
G
I
I
T
K
Q
A
K
K
_
_
Zebra Danio
Brachydanio rerio
XP_700468
242
27469
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P48461
327
37351
P316
S
S
G
R
P
L
T
P
P
R
G
A
N
N
K
Honey Bee
Apis mellifera
XP_392943
329
37410
P318
A
N
R
P
V
T
P
P
R
G
G
G
N
N
K
Nematode Worm
Caenorhab. elegans
P48727
333
37773
T317
V
G
S
N
R
P
V
T
P
P
R
N
A
P
A
Sea Urchin
Strong. purpuratus
XP_791029
330
37658
T318
G
G
S
G
R
P
V
T
P
P
R
G
T
N
N
Poplar Tree
Populus trichocarpa
Maize
Zea mays
P22198
316
35745
G301
K
P
A
R
K
M
M
G
G
S
T
N
N
K
S
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P48482
312
35513
Baker's Yeast
Sacchar. cerevisiae
P32598
312
35889
P303
K
P
A
Q
K
S
L
P
R
Q
A
G
G
R
K
Red Bread Mold
Neurospora crassa
Q9UW86
308
35549
Conservation
Percent
Protein Identity:
100
90.9
94
N.A.
N.A.
91.8
92.1
N.A.
88.1
99
99
58.2
N.A.
88.6
91.4
89.4
88.4
Protein Similarity:
100
90.9
94.9
N.A.
N.A.
94.2
94.2
N.A.
89.5
99.6
100
61.2
N.A.
93.5
94.2
93.6
93.6
P-Site Identity:
100
100
26.6
N.A.
N.A.
6.6
6.6
N.A.
100
92.3
92.3
0
N.A.
6.6
0
6.6
6.6
P-Site Similarity:
100
100
26.6
N.A.
N.A.
13.3
13.3
N.A.
100
92.3
100
0
N.A.
26.6
6.6
13.3
13.3
Percent
Protein Identity:
N.A.
73
N.A.
74.9
81.7
82.3
Protein Similarity:
N.A.
83.9
N.A.
84.2
89.4
89.7
P-Site Identity:
N.A.
20
N.A.
0
20
0
P-Site Similarity:
N.A.
26.6
N.A.
0
40
0
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
6
0
12
0
0
6
0
0
0
0
36
6
6
0
6
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
18
12
6
6
36
12
0
12
6
6
12
18
6
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
6
30
0
12
0
0
0
6
0
0
% I
% Lys:
12
0
0
0
12
0
0
0
30
0
0
30
30
6
24
% K
% Leu:
0
12
0
0
0
6
6
0
6
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
30
6
0
0
0
0
0
0
0
0
% M
% Asn:
0
6
12
6
0
0
0
0
0
6
0
12
18
30
6
% N
% Pro:
0
48
36
18
6
12
6
30
18
12
18
12
0
6
0
% P
% Gln:
0
0
0
6
0
0
0
0
0
36
0
0
0
6
0
% Q
% Arg:
0
0
6
48
12
0
12
0
12
6
12
0
12
6
0
% R
% Ser:
6
6
12
0
6
6
6
0
0
6
0
6
0
0
18
% S
% Thr:
36
0
0
0
0
6
6
42
0
12
6
0
6
0
0
% T
% Val:
6
0
0
0
12
0
12
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
30
30
% _