KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FLT3
All Species:
13.64
Human Site:
S740
Identified Species:
30
UniProt:
P36888
Number Species:
10
Phosphosite Substitution
Charge Score:
0.5
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P36888
NP_004110.2
993
112903
S740
P
N
S
S
M
P
G
S
R
E
V
Q
I
H
P
Chimpanzee
Pan troglodytes
XP_509601
993
112798
S740
P
N
S
S
M
P
G
S
R
E
V
Q
I
H
P
Rhesus Macaque
Macaca mulatta
XP_001117913
993
112706
S740
P
N
S
S
M
P
G
S
R
D
V
Q
I
H
P
Dog
Lupus familis
XP_546306
967
107148
D709
E
K
K
Y
V
R
R
D
S
G
F
S
S
Q
G
Cat
Felis silvestris
Mouse
Mus musculus
Q00342
992
112621
S741
S
N
S
S
M
P
G
S
R
E
V
Q
L
H
P
Rat
Rattus norvegicus
Q00495
978
109246
D710
E
K
K
Y
V
R
R
D
S
G
F
S
S
Q
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001519582
987
111585
S740
Y
P
R
L
H
L
H
S
N
T
S
T
H
D
F
Chicken
Gallus gallus
Q08156
960
107293
E705
P
T
A
D
A
V
N
E
Y
M
D
M
K
P
G
Frog
Xenopus laevis
Q91909
954
106841
E707
M
G
C
E
G
M
S
E
Y
I
D
M
K
P
A
Zebra Danio
Brachydanio rerio
Q8JFR5
976
109261
M710
S
R
N
G
Y
M
T
M
K
P
S
V
L
G
I
Tiger Blowfish
Takifugu rubipres
P79750
975
110895
D715
Q
K
W
Y
I
R
S
D
S
G
I
S
S
T
S
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.9
96.4
30.3
N.A.
83.9
29.6
N.A.
66.8
31.5
30.7
33.8
30.6
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.5
98.4
48.5
N.A.
89.7
47.6
N.A.
80.5
48.4
46.6
49.7
47.4
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
93.3
0
N.A.
86.6
0
N.A.
6.6
6.6
0
0
0
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
6.6
N.A.
93.3
6.6
N.A.
6.6
13.3
0
20
13.3
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
10
0
10
0
0
0
0
0
0
0
0
0
10
% A
% Cys:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
10
0
0
0
28
0
10
19
0
0
10
0
% D
% Glu:
19
0
0
10
0
0
0
19
0
28
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
19
0
0
0
10
% F
% Gly:
0
10
0
10
10
0
37
0
0
28
0
0
0
10
28
% G
% His:
0
0
0
0
10
0
10
0
0
0
0
0
10
37
0
% H
% Ile:
0
0
0
0
10
0
0
0
0
10
10
0
28
0
10
% I
% Lys:
0
28
19
0
0
0
0
0
10
0
0
0
19
0
0
% K
% Leu:
0
0
0
10
0
10
0
0
0
0
0
0
19
0
0
% L
% Met:
10
0
0
0
37
19
0
10
0
10
0
19
0
0
0
% M
% Asn:
0
37
10
0
0
0
10
0
10
0
0
0
0
0
0
% N
% Pro:
37
10
0
0
0
37
0
0
0
10
0
0
0
19
37
% P
% Gln:
10
0
0
0
0
0
0
0
0
0
0
37
0
19
0
% Q
% Arg:
0
10
10
0
0
28
19
0
37
0
0
0
0
0
0
% R
% Ser:
19
0
37
37
0
0
19
46
28
0
19
28
28
0
10
% S
% Thr:
0
10
0
0
0
0
10
0
0
10
0
10
0
10
0
% T
% Val:
0
0
0
0
19
10
0
0
0
0
37
10
0
0
0
% V
% Trp:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
10
0
0
28
10
0
0
0
19
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _